Evidence map›Paper›PMID 24872115›Full record

ArticleJournal of clinical and experimental neuropsychology2014

Hemispheric side of damage influences sex-related differences in smoking cessation in neurological patients.

Natassia Gaznick, Antoine Bechara, Daniel Tranel

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sex Differences in the Long-Term Consequences of Stroke.Current topics in behavioral neurosciences · 2023
    Review
  2. A Neurobehavioral Approach to Addiction: Implications for the Opioid Epidemic and the Psychology of Addiction.Psychological science in the public interest : a journal of the American Psychological Society · 2019
    Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Natassia Gaznicka Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience , Tranel Lab, University of Iowa , Iowa City , IA , USA.
Antoine Bechara
Daniel Tranel
University of Iowa · USUniversity of Southern California · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
Neuroeconomics and decision-makingP50NS019632 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANDERSON, STEVEN W · 2008 to 2011
$5.1M
Changes in Addictive Behaviors After Brain LesionsR01DA023051 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BECHARA, ANTOINE · 2008 to 2012
$2.4M
Drug Abuse, Social Decision-Making, and Sex-Related Functional Brain AsymmetryR01DA022549 · NIDA · UNIVERSITY OF IOWA · PI TRANEL, DANIEL T. · 2006 to 2010
$1.7M
NIDA NIH HHS R01 DA022549NIDA NIH HHS R01 DA023051NIGMS NIH HHS T32 GM007337NINDS NIH HHS P50 NS019632NINDS NIH HHS P50 NS19632
6 · The paper itself

Abstract

Patterns of smoking behavior vary between the sexes. There is evidence that decision making, which is one of the key "executive functions" necessary for making life-style modifications such as smoking cessation, is relatively lateralized to the right hemisphere in males and left hemisphere in females. In the current study, we examined whether the side of brain lesion has a differential effect on smoking behavior between the sexes. We hypothesized sex differences in smoking cessation based on lesion side. Participants were 49 males and 50 females who were smoking at the time of lesion onset. The outcome variable was abstinence from smoking (quit rate) at least one year post lesion. We found that in patients with left-hemisphere damage, quit rates were significantly higher in males than in females; however, in patients with right-hemisphere damage, quit rates were not statistically different. The findings support previous cognitive neuroscience literature showing that components of behavior responsible for maintaining addiction tend to be more strongly lateralized in males, whereas in females there is a more bilateral distribution. Our study provides further evidence for differences in lateralization of complex behavior between the sexes, which has significant implications for differences in treatment strategies between the sexes.

Indexed as

AdultAgedBrainFemaleFunctional LateralityHumansMaleMiddle AgedSex CharacteristicsSmokingSmoking CessationStrokeAddictionBehavior lateralizationDrug abuseGender differencesSmoking cessation

Identifiers

PMID24872115
PMCPMC4052374
OpenAlexW2115361178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.