Evidence map›Paper›PMID 24871666›Full record

Trial reportGastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

A high-fiber diet may improve bowel function and health-related quality of life in patients with Crohn disease.

Carol S Brotherton, Ann Gill Taylor, Cheryl Bourguignon, Joel G Anderson

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
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  17. British Dietetic Association consensus guidelines on the nutritional assessment and dietary management of patients with inflammatory bowel disease.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Article
  18. Review
  19. Review
  20. Diets for inflammatory bowel disease: What do we know so far?European journal of clinical nutrition · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carol S BrothertonCarol S. Brotherton, PhD, MSN, RN, is Research Associate, Center for the Study of Complementary and Alternative Therapies, University of Virginia, Charlottesville, Virginia. Ann Gill Taylor, EdD, MS, RN, FAAN, is Center Director, Center for the Study of Complementary and Alternative Therapies, University of Virginia, Charlottesville, Virginia. Cheryl Bourguignon, PhD, RN, is Associate Professor of Nursing and Statistician, Center for the Study of Complementary and Alternative Therapies, University of Virginia, Charlottesville, Virginia. Joel G. Anderson, PhD, HTP, is Assistant Professor, Center for the Study of Complementary and Alternative Therapies, School of Nursing, Nursing of University of Virginia, Charlottesville, Virginia.
Ann Gill Taylor
Cheryl Bourguignon
Joel G Anderson
U.S. National Science Foundation · US

Funding

Dietary Support for Healthy Digestion in Crohn's DiseaseF31NR011121 · NINR · UNIVERSITY OF VIRGINIA · PI BROTHERTON, CAROL S. · 2008 to 2011
$107k
NINR NIH HHS 5-F31-NR011121NINR NIH HHS F31 NR011121
6 · The paper itself

Abstract

Crohn disease is a chronic disorder characterized by episodes of epithelial inflammation in the gastrointestinal tract for which there is no cure. The prevalence of Crohn disease increased in civilized nations during the time period in which food sources were industrialized in those nations. A characteristic of industrialized diets is the conspicuous absence of cereal fiber. The purpose of this 2-group, randomized, controlled study was to investigate the effects of fiber-related dietary instructions specifying wheat bran consumption on health-related quality of life and gastrointestinal function in individuals diagnosed with Crohn disease, as measured by the Inflammatory Bowel Disease Questionnaire and the partial Harvey Bradshaw Index, respectively. Results demonstrated that consuming a wheat bran-inclusive diet was feasible and caused no adverse effects, and participants consuming whole wheat bran in the diet reported improved health-related quality of life (p = .028) and gastrointestinal function (p = .008) compared to the attention control group. The results of a secondary aim, to investigate differences in measures of systemic inflammation, found no group differences in C-reactive protein or erythrocyte sedimentation rates. This study suggests that diet modification may be a welcomed complementary therapy for individuals suffering gastrointestinal disruption associated with Crohn disease.

Indexed as

Quality of LifeAdolescentAdultBiomarkersC-Reactive ProteinCrohn DiseaseDietary FiberFeasibility StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsSingle-Blind MethodSurveys and QuestionnairesTreatment OutcomeBiomarkersC-Reactive ProteinDietary Fiber

Identifiers

PMID24871666
PMCPMC4260718
OpenAlexW2075570032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.