ArticleClinical research in cardiology : official journal of the German Cardiac Society2014
ICD therapy for primary prevention of sudden cardiac death after Mustard repair for d-transposition of the great arteries.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Implantable cardioverter-defibrillators in adults with congenital heart disease: a systematic review and meta-analysis.European heart journal · 2016Pooled it
- Long-time "real-life" performance of the subcutaneous ICD in patients with electrical heart disease or idiopathic ventricular fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2016Trial
- Long-Term Results After Senning and Mustard Operations for d-Transposition of the Great Arteries: Atrial Switch Should Remain in Armamentarium.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026Article
- Implantable Cardioverter-Defibrillator Therapy in Patients With Transposition of the Great Arteries: A Systematic Review of the Literature.CJC pediatric and congenital heart disease · 2025Review
- Fate After the Mustard Procedure for d-Transposition of the Great Arteries: Impact of Age, Complexity, and Atrial Tachyarrhythmias: A Single Center Experience.Pediatric cardiology · 2023Article
- Myocardial fibrosis and its relation to adverse outcome in transposition of the great arteries with a systemic right ventricle.International journal of cardiology · 2018Article
- Implantable cardioverter defibrillator therapy in grown-up patients with transposition of the great arteries-role of anti-tachycardia pacing.Journal of thoracic disease · 2018Article
- When left turns to right: a congenital corrected transposition of the great arteries with an azygos continuation without another major cardiac abnormality.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Intraoperative Defibrillation Testing of Subcutaneous Implantable Cardioverter-Defibrillator Systems-A Simple Issue?Journal of the American Heart Association · 2016Article
- Long-term follow-up of subcutaneous ICD systems in patients with hypertrophic cardiomyopathy: a single-center experience.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Limitations in S-ICD therapy: reasons for system explantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Radial artery applanation tonometry for continuous noninvasive arterial blood pressure monitoring in the cardiac intensive care unit.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundYears and decades after the Mustard atrial switch repair for d-Transposition of the great arteries, there is a subset of patients at increased risk for sudden cardiac death due to ventricular tachyarrhythmias. To date, little is known about indications, efficacy and benefit of internal cardioverter defibrillator (ICD) therapy indication in these patients. PATIENTS/
methodsTo characterize the Mustard patients already treated with an ICD, we conducted a single center case control study (n = 41). The charts of all patients after Mustard procedure at our institution were systematically reviewed for history, echocardiographic findings, arrhythmias, hemodynamics and medication as well as ICD discharges and complications.
resultsSignificant differences between ICD (n = 12) and non-ICD patients (n = 29) were found regarding the stage of heart failure, need for heart failure medication, QRS duration and left ventricular diameter and performance. Inappropriate ICD discharges due to rapidly conducted atrial reentrant tachycardia and sensing failure were frequently observed. In 17 % of our Mustard patients with an ICD, infection of the implantation site required surgical revision. All ICD patients were of male gender.
conclusionPatients after ICD implantation represent a subgroup among our Mustard patients with a more advanced state of cardiac disease. Not only systemic right ventricular diameter and performance but also subpulmonary left ventricular performance was an important factor predicting the long-term course of these patients. Prevention of inappropriate discharges requires decent device programming, close monitoring of lead integrity and treatment of atrial tachycardias.
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