ArticleACS nano2014
Lung macrophages "digest" carbon nanotubes using a superoxide/peroxynitrite oxidative pathway.
Article in ACS nano, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Exploring the potential relationship between serum biomarkers in obese individuals and cancer using FTIR, metabolomics, and lipidomics.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Biodegradation of Heterogeneous Industrial Multi-Walled Carbon Nanotubes by Pro-Inflammatory Macrophages.Nanomaterials (Basel, Switzerland) · 2024Article
- Patterns of Carbon-Bound Exogenous Compounds Impact Disease Pathophysiology in Lung Cancer Subtypes in Different Ways.ACS nano · 2023Article
- Short-Term Intravenous Administration of Carbon Nano-Onions is Non-Toxic in Female Mice.International journal of nanomedicine · 2023Article
- Colloidal Behavior and Biodegradation of Engineered Carbon-Based Nanomaterials in Aquatic Environment.Nanomaterials (Basel, Switzerland) · 2022Review
- Pulmonary Fibrosis Induced by CdSe Nanorods and the Therapy with Modified Procyanidinere.Toxics · 2022Article
- Nitrogen-Doped Carbon Nanotube Cups for Cancer Therapy.ACS applied nano materials · 2022Article
- Immunotoxicity of Carbon-Based Nanomaterials, Starring Phagocytes.International journal of molecular sciences · 2022Review
- Detection of HOCl-driven degradation of the pericardium scaffolds by label-free multiphoton fluorescence lifetime imaging.Scientific reports · 2022Article
- A New Look at the Effects of Engineered ZnO and TiONanomaterials (Basel, Switzerland) · 2022Review
- Gold Nanoparticles Dissolve Extracellularly in the Presence of Human Macrophages.International journal of nanomedicine · 2021Article
- Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution.Environmental health perspectives · 2020Article
- Mitigation of Carbon Nanotube Neurosensor Induced Transcriptomic and Morphological Changes in Mouse Microglia with Surface Passivation.ACS nano · 2020Article
- Size-Dependent Pulmonary Impact of Thin Graphene Oxide Sheets in Mice: Toward Safe-by-Design.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Clearance of single-wall carbon nanotubes from the mouse lung: a quantitative evaluation.Nanoscale advances · 2020Article
- The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention.Frontiers in bioengineering and biotechnology · 2020Article
- Biotransformation of Pristine and Oxidized Carbon Nanotubes by the White Rot FungusNanomaterials (Basel, Switzerland) · 2019Article
- Nano-bio interactions: a neutrophil-centric view.Cell death & disease · 2019Review
- Time-dependent degradation of carbon nanotubes correlates with decreased reactive oxygen species generation in macrophages.International journal of nanomedicine · 2019Article
- The Role of Cardiolipin and Mitochondrial Damage in Kidney Transplant.Oxidative medicine and cellular longevity · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
In contrast to short-lived neutrophils, macrophages display persistent presence in the lung of animals after pulmonary exposure to carbon nanotubes. While effective in the clearance of bacterial pathogens and injured host cells, the ability of macrophages to "digest" carbonaceous nanoparticles has not been documented. Here, we used chemical, biochemical, and cell and animal models and demonstrated oxidative biodegradation of oxidatively functionalized single-walled carbon nanotubes via superoxide/NO* → peroxynitrite-driven oxidative pathways of activated macrophages facilitating clearance of nanoparticles from the lung.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.