Evidence map›Paper›PMID 24870569›Full record

ArticleMedicine and science in sports and exercise2015

Effects of exercise and weight loss in older adults with obstructive sleep apnea.

Devon A Dobrosielski, Susheel Patil, Alan R Schwartz, Karen Bandeen-Roche, Kerry J Stewart

Open access · greenAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Trial
  3. The effects of exercise training as a treatment component of obstructive sleep apnea in diverse patient groups: current understanding and focus areas.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  4. Article
  5. Article
  6. Sleep disorders and exercise: a mini-review.Journal of thoracic disease · 2023
    Review
  7. Review
  8. Article
  9. Predictors of Sleep Apnea in the Canadian Population.Canadian respiratory journal · 2018
    Article
  10. Article
  11. Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  12. Article
  13. Consensus & evidence-based INOSA Guidelines 2014 (first edition).The Indian journal of medical research · 2014
    Article
  14. The role of physical exercise in obstructive sleep apnea.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Devon A Dobrosielski1Department of Kinesiology, Towson University, Towson, MD; 2Department of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD; 3Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore MD; and 4Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Susheel Patil
Alan R Schwartz
Karen Bandeen-Roche
Kerry J Stewart
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
NCATS NIH HHS UL1 TR001079NCRR NIH HHS UL1 RR025005NCRR NIH HHS UL 1RR025005NIA NIH HHS P30 AG021334
6 · The paper itself

Abstract

purposeObstructive sleep apnea (OSA) is prevalent among older individuals and is linked to increased cardiovascular disease morbidity. This study examined the change in OSA severity after exercise training and dietary-induced weight loss in older adults and the association of the changes in OSA severity, body composition, and aerobic capacity with arterial distensibility.

methodsObese adults (n = 25) with OSA, age 60 yr or older, were instructed to participate in supervised exercise (3 d·wk) and follow a calorie-restricted diet. Baseline assessments of OSA parameters, body weight and composition, aerobic capacity, and arterial distensibility were repeated at 12 wk.

resultsNineteen participants completed the intervention. At 12 wk, there were reductions in body weight (-9%) and percentage of total body fat (-5%) and trunk fat (-8%) whereas aerobic capacity improved by 20% (all P < 0.01). The apnea-hypopnea index decreased by 10 events per hour (P < 0.01) and nocturnal SaO2 (mean SaO2) improved from 94.9% at baseline to 95.2% after intervention (P = 0.01). Arterial distensibility for the group was not different from that at baseline (P = 0.99), yet individual changes in distensibility were associated with the change in nocturnal desaturations (r = -0.49, P = 0.03) but not with the change in body weight, apnea-hypopnea index, or aerobic capacity.

conclusionsThe severity of OSA was reduced after an exercise and weight loss program among older adults, suggesting that this lifestyle approach may be an effective first-line nonsurgical and nonpharmacological treatment for older patients with OSA.

Indexed as

Caloric RestrictionDiet, ReducingWeight LossAdiposityAgedAnaerobic ThresholdExerciseFemaleHumansMaleMiddle AgedObesityOxygenSeverity of Illness IndexSleep Apnea, ObstructiveVascular StiffnessOxygen

Identifiers

PMID24870569
PMCPMC4246024
OpenAlexW2014035588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.