ArticleProceedings. Biological sciences2014
Host ecotype generates evolutionary and epidemiological divergence across a pathogen metapopulation.
Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 64 citations in OpenAlex.
- Phyllosphere pathogen diversity and leaf functional traits covary at a local scale in subtropical forests.BMC ecology and evolution · 2025Article
- Structuring of plant communities across agricultural landscape mosaics: the importance of connectivity and the scale of effect.BMC ecology and evolution · 2021Article
- Genetic analysis reveals long-standing population differentiation and high diversity in the rust pathogen Melampsora lini.PLoS pathogens · 2020Article
- Novel Insights reveal Anti-microbial Gene Regulation of Piglet Intestine Immune in response to Clostridium perfringens Infection.Scientific reports · 2019Article
- Conservation of Endophyte Bacterial Community Structure Across TwoFrontiers in microbiology · 2019Article
- Foliar fungal endophyte communities are structured by environment but not host ecotype in Panicum virgatum (switchgrass).Ecology · 2018Article
- Gene Presence-Absence Polymorphism in Castrating Anther-Smut Fungi: Recent Gene Gains and Phylogeographic Structure.Genome biology and evolution · 2018Article
- Evolution and genome architecture in fungal plant pathogens.Nature reviews. Microbiology · 2017Review
- Temporal patterns of local adaptation in soil pseudomonads.Proceedings. Biological sciences · 2016Article
- The role of evolutionary biology in research and control of liver flukes in Southeast Asia.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016Review
- Understanding the ecology and evolution of host-parasite interactions across scales.Evolutionary applications · 2016Review
- Below-ground abiotic and biotic heterogeneity shapes above-ground infection outcomes and spatial divergence in a host-parasite interaction.The New phytologist · 2015Article
- Spatial heterogeneity lowers rather than increases host-parasite specialization.Journal of evolutionary biology · 2015Article
- Specialization for resistance in wild host-pathogen interaction networks.Frontiers in plant science · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The extent and speed at which pathogens adapt to host resistance varies considerably. This presents a challenge for predicting when--and where--pathogen evolution may occur. While gene flow and spatially heterogeneous environments are recognized to be critical for the evolutionary potential of pathogen populations, we lack an understanding of how the two jointly shape coevolutionary trajectories between hosts and pathogens. The rust pathogen Melampsora lini infects two ecotypes of its host plant Linum marginale that occur in close proximity yet in distinct populations and habitats. In this study, we found that within-population epidemics were different between the two habitats. We then tested for pathogen local adaptation at host population and ecotype level in a reciprocal inoculation study. Even after controlling for the effect of spatial structure on infection outcome, we found strong evidence of pathogen adaptation at the host ecotype level. Moreover, sequence analysis of two pathogen infectivity loci revealed strong genetic differentiation by host ecotype but not by distance. Hence, environmental variation can be a key determinant of pathogen population genetic structure and coevolutionary dynamics and can generate strong asymmetry in infection risks through space.
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