ReviewWorld journal of nephrology2014
Pediatric lupus nephritis: Management update.
Review in World journal of nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- The Evolution of Lupus Nephritis Therapy from the 1960s to the Present.Bioengineering (Basel, Switzerland) · 2026Review
- Evaluation of Hypertension in Pediatric Patients With Systemic Lupus Erythematosus: A Historical Study.International journal of hypertension · 2026Article
- Insights into pediatric lupus nephritis: clinical features and short-term outcomes from a single center retrospective study.BMC nephrology · 2025Article
- Prognostic Value of the 2019 EULAR/American College of Rheumatology Systemic Lupus Erythematosus Classification Criteria to Renal Response One Year After Treatment in a Cohort With Childhood-Onset Lupus Nephritis.ACR open rheumatology · 2024Article
- Comparison of Histomorphological Indices Between Adult and Pediatric Patients in Response to Induction Therapy.Cureus · 2024Article
- A rare case of childhood-onset systemic lupus erythematosus associated end-stage renal disease with cerebral abscess and hemorrhage.Childhood kidney diseases · 2024Article
- Renal Thrombotic Microangiopathy: A Complication of Paediatric Systemic Lupus Erythematosus That Requires Attention.Cureus · 2023Article
- Clinicopathological, Immunological, and Laboratory Parameters of Childhood Lupus Nephritis: A Study from Northeast India.Journal of laboratory physicians · 2023Article
- Clinical and histopathological study of renal biopsy in Nepalese children: A single center experience.PloS one · 2022Article
- Systemic lupus erythematosus complicated by a Gitelman-like syndrome in an 8-year-old girl.CEN case reports · 2020Article
- Effect of Mental Health Problems on the Quality of Life in Children with Lupus Nephritis.Neuropsychiatric disease and treatment · 2020Article
- The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis.Scientific reports · 2019Article
- Hematuria and Proteinuria in Children.Pediatrics in review · 2018Review
- Treatment of pediatric-onset lupus nephritis: a proposal of optimal therapy.Clinical and experimental nephrology · 2017Review
- Clinicopathological findings and outcome of lupus nephritis in Tunisian children: a review of 43 patients.The Pan African medical journal · 2017Article
- An Update on Treatment and Management of Pediatric Systemic Lupus Erythematosus.Rheumatology and therapy · 2016Review
- Reviewing the recommendations for lupus in children.Current rheumatology reports · 2015Review
- Pediatric lupus nephritis.Jornal brasileiro de nefrologiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood-onset systemic lupus erythematosus (cSLE) is a severe multisystem autoimmune disease. Renal involvement occurs in the majority of cSLE patients and is often fatal. Renal biopsy is an important investigation in the management of lupus nephritis. Treatment of renal lupus consists of an induction phase and maintenance phase. Treatment of childhood lupus nephritis using steroids is associated with poor outcome and excess side-effects. The addition of cyclophosphamide to the treatment schedule has improved disease control. In view of treatment failure using these drugs and a tendency for non-adherence, many newer agents such as immune-modulators and monoclonal antibodies are being tried in patients with cSLE. Trials of these novel agents in the pediatric population are still lacking making a consensus in the management protocol of pediatric lupus nephritis difficult.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.