Evidence map›Paper›PMID 24868494›Full record

ReviewTissue barriers2013

Phosphatase regulation of intercellular junctions.

Declan F McCole

Open access · bronzeAbstract readReview
In one paragraph

Review in Tissue barriers, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Role of Nuclear Claudin-4 in Renal Cell Carcinoma.International journal of molecular sciences · 2020
    Article
  6. Cooperative Interactions betweenInfection and immunity · 2019
    Article
  7. Frontiers in cellular and infection microbiology · 2017
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Declan F McColeDivision of Biomedical Sciences; University of California, Riverside; Riverside, CA USA.
University of California, Riverside · US

Funding

A NOVEL ROLE FOR PTPN2 IN INTESTINAL EPITHELIAL BARRIER REGULATIONR01DK091281 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Declan McCole · 2012 to 2026
$5.5M
Novel Effects of Gravity on Intestinal Epithelial Barrier Responses to AlcoholUH2AA019708 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCOLE, DECLAN · 2010 to 2011
$439k
NIAAA NIH HHS UH2 AA019708NIDDK NIH HHS R01 DK091281
6 · The paper itself

Abstract

Intercellular junctions represent the key contact points and sites of communication between neighboring cells. Assembly of these junctions is absolutely essential for the structural integrity of cell monolayers, tissues and organs. Disruption of junctions can have severe consequences such as diarrhea, edema and sepsis, and contribute to the development of chronic inflammatory diseases. Cell junctions are not static structures, but rather they represent highly dynamic micro-domains that respond to signals from the intracellular and extracellular environments to modify their composition and function. This review article will focus on the regulation of tight junctions and adherens junctions by phosphatase enzymes that play an essential role in preserving and modulating the properties of intercellular junction proteins.

Indexed as

adherens junctioncadherinsclaudinsoccludinpermeabilityphosphorylationtight junction

Identifiers

PMID24868494
PMCPMC4002623
OpenAlexW2057725572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.