Evidence map›Paper›PMID 24868459›Full record

ArticleJournal of ophthalmology2014

Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet's Disease with Spectral-Domain OCT.

Mustafa Ataş, Isa Yuvacı, Süleyman Demircan, Emel Güler, Orhan Altunel, Emine Pangal, Altan Göktaş, Serap Sütbeyaz, Gökmen Zararsız

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  13. Validation of Macular Choroidal Thickness Measurements from Automated SD-OCT Image Segmentation.Optometry and vision science : official publication of the American Academy of Optometry · 2016
    Article
  14. Article
  15. Retinal nerve fiber layer structure abnormalities in patients with Neuro-Behcet's disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015
    Article
  16. Article
  17. Clinical Features of Behçet's Disease Uveitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mustafa AtaşDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Isa YuvacıDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Süleyman DemircanDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Emel GülerDepartment of Physical Medicine and Rehabilitation, Kayseri Research and Teaching Hospital, Turkey.
Orhan AltunelDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Emine PangalDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Altan GöktaşDepartment of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey.
Serap SütbeyazDepartment of Physical Medicine and Rehabilitation, Kayseri Research and Teaching Hospital, Turkey.
Gökmen ZararsızDepartment of Biostatistics, Medical School, University of Erciyes, Turkey.
Kayseri Eğitim ve Araştırma Hastanesi · TRErciyes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose. To assess the macular, choroid, and peripapillary nerve fiber layer thickness (RNFL) in Behçet's disease (BD) patients with and without ocular involvement by means of optical coherence tomography (OCT) and compare these findings with healthy controls. Design. Eighty patients with BD and 40 healthy controls who were followed up at the Uveitis and Retina Clinic of the Kayseri Research and Education Hospital in Turkey were enrolled in this prospective study. Subjects and Controls. The patients with BD were divided into two groups according to the presence of ocular involvement. Group 1 consisted of 40 eyes of 40 patients with ocular involvement and group 2 consisted of 40 eyes of 40 patients without ocular involvement. Methods. All of the patients and controls underwent macular, choroid, and peripapillary nerve fiber layer thickness analysis with Spectralis domain OCT (Spectralis OCT Heidelberg Engineering, Dossenheim, Germany). Main Outcome Measures. The differences in macular, choroid, and peripapillary nerve fiber layer thicknesses between groups were analyzed statistically. Results. Macular thickness was thinner in patients with BD than in the control group; this result was statistically significant (P = 0.05). There was no statistically significant difference in thickness between RNFL analysis of the patients with BD and control subjects. However, the BD patients with ocular involvement had statistically significant thinning in RNFL compared with BD patients without ocular involvement. Although the choroid was thicker in patients with BD than in the control group, it did not reach a statistically significant level (P = 0.382). Conclusions. BD with ocular involvement may be associated with decreased macular and RNFL thickness measured with spectral-domain OCT.

Identifiers

PMID24868459
PMCPMC4020218
OpenAlexW2099230154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.