Evidence map›Paper›PMID 24868332›Full record

ReviewKorean journal of urology2014

Penile low-intensity shock wave therapy: a promising novel modality for erectile dysfunction.

Yasmin Abu-Ghanem, Noam D Kitrey, Ilan Gruenwald, Boaz Appel, Yoram Vardi

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Korean journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06717711 (Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06717711 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers

TypeinterventionalSponsorRegina Elena Cancer InstituteRan2023 to 2028Enrolled158ConditionsProstate Carcinoma, Erectile Function, Genito Urinary CancerArmsLow-intensity Extracorporeal Shock Wave Therapy (LiESWT), PDE5 inhibitor (tadalafil)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Review
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  11. Review
  12. Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction - a narrative review.International braz j urol : official journal of the Brazilian Society of Urology
    Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yasmin Abu-GhanemDepartment of Urology, Sheba Medical Center, Ramat-Gan, Israel.
Noam D KitreyDepartment of Urology, Sheba Medical Center, Ramat-Gan, Israel.
Ilan GruenwaldNeuro-urology Unit, Rambam Health Campus, Haifa, Israel.
Boaz AppelNeuro-urology Unit, Rambam Health Campus, Haifa, Israel.
Yoram VardiDepartment of Urology, Sheba Medical Center, Ramat-Gan, Israel.
Sheba Medical Center · ILRambam Health Care Campus · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penile extracorporeal low-intensity shock wave therapy (LIST) to the penis has recently emerged as a novel and promising modality in the treatment of erectile dysfunction (ED). LIST has angiogenic properties and stimulates neovascularization. If applied to the corpora cavernosa, LIST can improve penile blood flow and endothelial function. In a series of clinical trials, including randomized double-blind sham-controlled studies, LIST has been shown to have a substantial effect on penile hemodynamics and erectile function in patients with vasculogenic ED. LIST is effective in patients who are responsive to phosphodiesterase 5 inhibitors (PDE5i) and can also convert PDE5i nonresponders to responders. The response to LIST wanes gradually over time, and after 2 years, about half of the patients maintain their function. Extensive research is needed to understand the effect of LIST on erectile tissue, to modify the treatment protocol to maximize its outcomes, and to identify the patients who will benefit the most from this treatment.

Indexed as

Erectile dysfunctionPenileShockwave treatmentTherapy

Identifiers

PMID24868332
PMCPMC4026654
OpenAlexW2122312839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.