ArticleWorld journal of hepatology2014
Central hepatectomy for centrally located malignant liver tumors: A systematic review.
Article in World journal of hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Central hepatectomy versus major hepatectomy for patients with centrally located hepatocellular carcinoma: a systematic review and meta-analysis.BMC surgery · 2023Pooled it
- Mesohepatectomy Versus Extended Hemihepatectomies for Centrally Located Liver Tumors: A Meta-Analysis.Scientific reports · 2017Pooled it
- Automatic Generation of Liver Virtual Models With Artificial Intelligence: Application to Liver Resection Complexity Prediction.Annals of surgery · 2026Article
- Advanced robotic liver surgery.Surgical endoscopy · 2026Review
- Laparoscopic central hepatectomy: Feasibility and safety.Surgical endoscopy · 2025Article
- C-reactive Protein-to-Albumin Ratio: A Useful Predictor for Biliary Fistula After Hepatectomy.Cureus · 2024Article
- Application of mesohepatectomy with caudate lobectomy for the treatment of type III-IV hilar cholangiocarcinoma: a single-center retrospective study.European journal of medical research · 2023Article
- Minimally invasive mesohepatectomy for centrally located liver lesions-a case series.Surgical endoscopy · 2022Article
- Parenchymal preserving liver resection for centrally located liver tumors: how I do it?Langenbeck's archives of surgery · 2022Article
- Early Prediction of Post-hepatectomy Liver Failure in Patients Undergoing Major Hepatectomy Using a PHLF Prognostic Nomogram.World journal of surgery · 2020Article
- Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma.Annals of hepato-biliary-pancreatic surgery · 2018Article
- Central Hepatectomy Still Plays an Important Role in Treatment of Early-Stage Centrally Located Hepatocellular Carcinoma.World journal of surgery · 2017Article
- Central Hepatectomy versus Extended Hepatectomy for Malignant Tumors: A Propensity Score Analysis of Postoperative Complications.World journal of surgery · 2016Article
- Central hepatectomy versus extended hepatectomy for liver malignancy: a matched cohort comparison.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Article
- Liver Resection and Surgical Strategies for Management of Primary Liver Cancer.Cancer control : journal of the Moffitt Cancer CenterReview
- CENTRAL HEPATECTOMY FOR BILIARY CYSTADENOMA: PARENCHYMA-SPARING APPROACH FOR BENIGN LESIONS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgeryArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study whether central hepatectomy (CH) can achieve similar overall patient survival and disease-free survival rates as conventional major hepatectomies or not.
methodsA systematic literature search was performed in MEDLINE for articles published from January 1983 to June 2013 to evaluate the evidence for and against CH in the management of central hepatic malignancies and to compare the perioperative variables and outcomes of CH to lobar/extended hemihepatectomy.
resultsA total of 895 patients were included from 21 relevant studies. Most of these patients who underwent CH were a sub-cohort of larger liver resection studies. Only 4 studies directly compared Central vs hemi-/extended hepatectomies. The range of operative time for CH was reported to be 115 to 627 min and Pringle's maneuver was used for vascular control in the majority of studies. The mean intraoperative blood loss during CH ranged from 380 to 2450 mL. The reported morbidity rates ranged from 5.1% to 61.1%, the most common surgical complication was bile leakage and the most common cause of mortality was liver failure. Mortality ranged from 0.0% to 7.1% with an overall mortality of 2.3% following CH. The 1-year overall survival (OS) for patients underwent CH for hepatocellular carcinoma ranged from 67% to 94%; with the 3-year and 5-year OS having a reported range of 44% to 66.8%, and 31.7% to 66.8% respectively.
conclusionBased on current literature, CH is a promising option for anatomical parenchymal-preserving procedure in patients with centrally located liver malignancies; it appears to be safe and comparable in both perioperative, early and long term outcomes when compared to patients undergoing hemi-/extended hepatectomy. More prospective studies are awaited to further define its role.
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