Trial reportClinical interventions in aging2014
Development of comorbidity-adapted exercise protocols for patients with knee osteoarthritis.
Trial report in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: the need to present minimal important differences units in meta-analyses.Health and quality of life outcomes · 2018Pooled it
- Barriers and facilitators of physical activity in knee and hip osteoarthritis: a systematic review of qualitative evidence.BMJ open · 2017Pooled it
- Effect of Preoperative Home-Based Exercise Training on Quality of Life After Lung Cancer Surgery: A Multicenter Randomized Controlled Trial.Annals of surgical oncology · 2024Trial
- Article
- Home-based cardiac rehabilitation in older adults: expert-recommendations for physiotherapist-led care to improve daily physical functioning and reduce comorbidity-related barriers.European journal of physiotherapy · 2024Article
- Psychologically informed health care.Translational behavioral medicine · 2023Article
- Home-Based Preoperative Exercise Training for Lung Cancer Patients Undergoing Surgery: A Feasibility Trial.Journal of clinical medicine · 2023Article
- Smartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E): study protocol for a multicentre pragmatic randomized controlled trial.BMC musculoskeletal disorders · 2023Article
- A mixed-methods feasibility study of a comorbidity-adapted exercise program for low back pain in older adults (COMEBACK): a protocol.Pilot and feasibility studies · 2022Article
- Article
- The trajectories of depression symptoms and comorbidity in knee osteoarthritis subjects.Clinical rheumatology · 2022Article
- Depression in Osteoarthritis: Current Understanding.Neuropsychiatric disease and treatment · 2022Review
- Article
- Geospatial patterns of comorbidity prevalence among people with osteoarthritis in Alberta Canada.BMC public health · 2020Article
- The association between comorbidity and physical activity levels in people with osteoarthritis: Secondary analysis from two randomised controlled trials.Osteoarthritis and cartilage open · 2020Article
- Evaluation of an educational course for primary care physiotherapists on comorbidity-adapted exercise therapy in knee osteoarthritis: an observational study.Musculoskeletal care · 2020Observational
- The effect and safety of exercise therapy in patients with systemic sclerosis: a systematic review.Rheumatology advances in practice · 2019Review
- A Biobehavioral Framework to Address the Emerging Challenge of Multimorbidity.Psychosomatic medicine · 2016Review
- Comorbidities and their link with individual health status: A cross-sectional analysis of 23,892 people with knee and hip osteoarthritis from primary care.Journal of comorbidityArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise therapy is generally recommended for patients with osteoarthritis (OA) of the knee. Comorbidity, which is highly prevalent in OA, may interfere with exercise therapy. To date, there is no evidence-based protocol for the treatment of patients with knee OA and comorbidity. Special protocols adapted to the comorbidity may facilitate the application of exercise therapy in patients with knee OA and one or more comorbidities. PURPOSE: The purpose of this study was to develop comorbidity-adapted exercise protocols for patients with knee OA and comorbidity.
methodSeveral steps were undertaken to develop comorbidity-adapted protocols: selection of highly prevalent comorbidities in OA, a literature search to identify restrictions and contraindications for exercise therapy for the various comorbid diseases, consultation of experts on each comorbid disease, and field testing of the protocol in eleven patients with knee OA and comorbidity.
resultsBased on literature and expert opinion, comorbidity-adapted protocols were developed for highly prevalent comorbidities in OA. Field testing showed that the protocols provided guidance in clinical decision making in both the diagnostic and the treatment phase. Because of overlap, the number of exercise protocols could be reduced to three: one for physiological adaptations (coronary disease, heart failure, hypertension, diabetes type 2, chronic obstructive pulmonary diseases, obesity), one for behavioral adaptations (chronic a-specific pain, nonspecific low back pain, depression), and one for environmental adaptations (visual or hearing impairments). Evaluation of patient outcome after treatment showed significant (P<0.05) and clinically relevant improvements in activity limitations and pain.
conclusionComorbidity-adapted exercise protocols for patients with knee OA were developed, providing guidance in clinical reasoning with regard to diagnostics and treatment. To evaluate the effectiveness of treatment in line with our protocols, a randomized clinical trial should be performed.
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