Multigene panel testing: planning the next generation of research studies in clinical cancer genetics.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. Preferences for in-person disclosure: Patients declining telephone disclosure characteristics and outcomes in the multicenter Communication Of GENetic Test Results by Telephone study.Clinical genetics · 2019
   Trial
2. Randomized Noninferiority Trial of Telephone vs In-Person Disclosure of Germline Cancer Genetic Test Results.Journal of the National Cancer Institute · 2018
   Trial
3. Germline Genetic Testing for Hereditary Breast and Ovarian Cancer: Current Concepts in Risk Evaluation.Cold Spring Harbor perspectives in medicine · 2024
   Review
4. Hereditary Diffuse Gastric Cancer: A 2022 Update.Journal of personalized medicine · 2022
   Review
5. Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations.Cancer · 2020
   Article
6. Metastatic Breast Cancer Coexisting With HER-2 Amplification and EGFR Exon 19 Deletion Benefits From EGFR-TKI Therapy: A Case Report.Frontiers in oncology · 2020
   Article
7. Diagnostic yield and clinical utility of a comprehensive gene panel for hereditary tumor syndromes.Hereditary cancer in clinical practice · 2019
   Article
8. Endometrial cancer gene panels: clinical diagnostic vs research germline DNA testing.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017
   Review
9. Outcomes of retesting BRCA negative patients using multigene panels.Familial cancer · 2017
   Article
10. Next-generation sequencing ofAnnals of surgical treatment and research · 2017
    Article
11. Payer Coverage for Hereditary Cancer Panels: Barriers, Opportunities, and Implications for the Precision Medicine Initiative.Journal of the National Comprehensive Cancer Network : JNCCN · 2017
    Article
12. Decision Making on Medical Innovations in a Changing Health Care Environment: Insights from Accountable Care Organizations and Payers on Personalized Medicine and Other Technologies.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2017
    Article
13. Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines.Hereditary cancer in clinical practice · 2017
    Review
14. Multi-gene panel testing for hereditary cancer susceptibility in a rural Familial Cancer Program.Familial cancer · 2017
    Observational
15. Incorporating truncating variants in PALB2, CHEK2, and ATM into the BOADICEA breast cancer risk model.Genetics in medicine : official journal of the American College of Medical Genetics · 2016
    Article
16. Advances in Hereditary Colorectal and Pancreatic Cancers.Clinical therapeutics · 2016
    Review
17. Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer.American journal of human genetics · 2016
    Article
18. A preliminary investigation of genetic counselors' information needs when receiving a variant of uncertain significance result: a mixed methods study.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Article
19. Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.Gastroenterology · 2015
    Article
20. Prioritizing therapeutic targets using patient-derived xenograft models.Biochimica et biophysica acta · 2015
    Review

Corrections and comments

• Comment on
  Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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