Evidence map›Paper›PMID 24867995›Full record

ReviewCirculation2014

Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis.

Francesca N Delling, Ramachandran S Vasan

Abstract readReview
In one paragraph

Review in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Incidence and type of recurrent ventricular arrhythmia in patients with arrhythmic mitral valve prolapse and implantable cardioverter defibrillator for secondary prevention.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  9. Regional strain patterns in patients with mitral valve prolapse.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  15. Immune Mechanisms of Heart Valve Development, Homeostasis, and Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026
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98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francesca N DellingFrom the Framingham Heart Study, Framingham, MA (F.N.D., R.S.V.); Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (F.N.D.); and Cardiology Section, and Preventive Medicine Section, Boston University School of Medicine, Boston, MA (R.S.V.). fdelling@bidmc.harvard.edu.
Ramachandran S VasanFrom the Framingham Heart Study, Framingham, MA (F.N.D., R.S.V.); Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (F.N.D.); and Cardiology Section, and Preventive Medicine Section, Boston University School of Medicine, Boston, MA (R.S.V.).

Funding

Ventricular Vascular Coupling: Correlates and PrognosisR01HL080124 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2005 to 2009
$3.4M
Aortic Dysfunction, Pulsatile Stress and Target Organ Damage in FraminghamR01HL107385 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MITCHELL, GARY FRANK, RAMACHANDRAN, VASAN S · 2011 to 2014
$2.6M
Genetic Determinants and Progression of Mitral Valve ProlapseK23HL116652 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DELLING, FRANCESCA N · 2014 to 2018
$699k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
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NHLBI NIH HHS K23 HL116652NHLBI NIH HHS K23HL116652NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NHLBI NIH HHS R01HL0107385NHLBI NIH HHS R01 HL080124NHLBI NIH HHS R01HL080124NHLBI NIH HHS R01 HL107385
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease ProgressionAnimalsHumansMitral Valve Prolapsemitral valvemitral valve insufficiencymitral valve prolapse

Identifiers

PMID24867995
PMCPMC4052751

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.