Evidence map›Paper›PMID 24866922›Full record

ArticleJournal of cancer survivorship : research and practice2014

Endocrine therapy initiation among Medicaid-insured breast cancer survivors with hormone receptor-positive tumors.

Stephanie Brooke Wheeler, Racquel Elizabeth Kohler, Katherine Elizabeth Reeder-Hayes, Ravi K Goyal, Kristen Hassmiller Lich, Alexis Moore, Timothy W Smith, Cathy L Melvin, Hyman Bernard Muss

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Stephanie Brooke WheelerDepartment of Health Policy and Management, University of North Carolina at Chapel Hill, 135 Dauer Drive, 1101 McGavran-Greenberg Hall, CB# 741,1, Chapel Hill, NC, 27599, USA, stephanie_wheeler@unc.edu.
Racquel Elizabeth Kohler
Katherine Elizabeth Reeder-Hayes
Ravi K Goyal
Kristen Hassmiller Lich
Alexis Moore
Timothy W Smith
Cathy L Melvin
Hyman Bernard Muss
University of North Carolina at Chapel Hill · USMedical University of South Carolina · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHARLES M PEROU · 1992 to 2026
$59.3M
Cancer Training GrantR25CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BASCH, ETHAN M., REEVE, BRYCE B · 2008 to 2017
$4.0M
UNC Mentored Career Development Program in Comparative Effectiveness ResearchK12HS019468 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2010 to 2010
$2.0M
AHRQ HHS 1-K-12 HS019468-01AHRQ HHS K12 HS019468NCI NIH HHS P30 CA016086NCI NIH HHS P50 CA058223NCI NIH HHS R25 CA116339
6 · The paper itself

Abstract

purposeHormone receptor-positive (HR+) cancers account for most breast cancer diagnoses and deaths. Among survivors with HR + breast cancers, endocrine therapy (ET) reduces 5-year risk of recurrence by up to 40%. Observational studies in Medicare- and privately-insured survivors suggest underutilization of ET. We sought to characterize ET use in a low-income Medicaid-insured population in North Carolina.

methodsMedicaid claims data were matched to state cancer registry records for survivors aging 18-64 diagnosed with stage 0-II HR + breast cancer from 2003 to 2007, eligible for ET, and enrolled in Medicaid for at least 12 of 15 months post-diagnosis. We used multivariable logistic regression to model receipt of any ET medication during 15 months post-diagnosis controlling for age, race, tumor characteristics, receipt of other treatments, comorbidity, residence, reason for Medicaid eligibility, involvement in the Breast and Cervical Cancer Control Program (BCCCP), and diagnosis year.

resultsOf 222 women meeting the inclusion criteria, only 50% filled a prescription for ET. Involvement in the BCCCP and earlier year of diagnoses were associated with significantly higher odds of initiating guideline-recommended ET (adjusted odds ratio [AOR] for the BCCCP 3.76, 95% confidence interval [CI] 1.67-8.48; AOR for 2004 relative to 2007 2.80, 95% CI 1.03-7.62; AOR for 2005 relative to 2007 2.11, 95% CI 0.92-4.85).

conclusionsResults suggest substantial underutilization of ET in this population. Interventions are needed to improve timely receipt of ET and to better support survivors taking ET. IMPLICATIONS FOR CANCER SURVIVORS: Low-income survivors should be counseled on the importance of ET and offered support services to promote initiation and long-term adherence.

Indexed as

Breast NeoplasmsFemaleHumansMedicaidMiddle AgedSurvivorsUnited States

Identifiers

PMID24866922
PMCPMC4970579
OpenAlexW2023920949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.