Evidence map›Paper›PMID 24866058›Full record

ArticlePublic health nutrition2015

Contribution of food sources to the vitamin B12 status of South Indian children from a birth cohort recruited in the city of Mysore.

Anna M Christian, Ghattu V Krishnaveni, Sarah H Kehoe, Sargoor R Veena, Rumana Khanum, Ella Marley-Zagar, Phil Edwards, Barrie M Margetts, Caroline Hd Fall

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Prevalence of Vitamin BIndian journal of pediatrics · 2017
    Article
  8. Prevalence of Vitamin B12 Deficiency and Its Associated Risk Factors among Pregnant Women of Rural South India: A Community-based Cross-sectional Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Anna M Christian1Faculty of Epidemiology and Population Health,London School of Hygiene & Tropical Medicine,London,UK.
Ghattu V Krishnaveni2Epidemiology Research Unit,CSI Holdsworth Memorial Hospital,Mysore,India.
Sarah H Kehoe3Medical Research Council Lifecourse Epidemiology Unit,University of Southampton,Southampton,UK.
Sargoor R Veena2Epidemiology Research Unit,CSI Holdsworth Memorial Hospital,Mysore,India.
Rumana Khanum2Epidemiology Research Unit,CSI Holdsworth Memorial Hospital,Mysore,India.
Ella Marley-Zagar3Medical Research Council Lifecourse Epidemiology Unit,University of Southampton,Southampton,UK.
Phil Edwards1Faculty of Epidemiology and Population Health,London School of Hygiene & Tropical Medicine,London,UK.
Barrie M Margetts4Faculty of Medicine,Primary Care and Population Sciences,University of Southampton,Southampton,UK.
Caroline Hd Fall3Medical Research Council Lifecourse Epidemiology Unit,University of Southampton,Southampton,UK.
CSI Holdsworth Memorial Hospital · INUniversity of Southampton · GBLondon School of Hygiene & Tropical Medicine · GBMedical Research Council · GB

Funding

Medical Research Council MC_U147574246Medical Research Council MC_UP_A620_1016Medical Research Council MC_UU_12011/3Medical Research Council MR/J000094/1Wellcome Trust 059609Wellcome Trust 079877Wellcome Trust 083460
6 · The paper itself

Abstract

objectiveThere is evidence that subclinical vitamin B12 (B12) deficiency is common in India. Vegetarianism is prevalent and therefore meat consumption is low. Our objective was to explore the contribution of B12-source foods and maternal B12 status during pregnancy to plasma B12 concentrations.

designMaternal plasma B12 concentrations were measured during pregnancy. Children's dietary intakes and plasma B12 concentrations were measured at age 9.5 years; B12 and total energy intakes were calculated using food composition databases. We used linear regression to examine associations between maternal B12 status and children's intakes of B12 and B12-source foods, and children's plasma B12 concentrations.

settingSouth Indian city of Mysore and surrounding rural areas. SUBJECTS: Children from the Mysore Parthenon Birth Cohort (n 512, 47.1 % male).

resultsThree per cent of children were B12 deficient (<150 pmol/l). A further 14 % had 'marginal' B12 concentrations (150-221 pmol/l). Children's total daily B12 intake and consumption frequencies of meat and fish, and micronutrient-enriched beverages were positively associated with plasma B12 concentrations (P=0.006, P=0.01 and P=0.04, respectively, adjusted for socio-economic indicators and maternal B12 status). Maternal pregnancy plasma B12 was associated with children's plasma B12 concentrations, independent of current B12 intakes (P<0.001). Milk and curd (yoghurt) intakes were unrelated to B12 status.

conclusionsMeat and fish are important B12 sources in this population. Micronutrient-enriched beverages appear to be important sources in our cohort, but their high sugar content necessitates care in their recommendation. Improving maternal B12 status in pregnancy may improve Indian children's status.

Indexed as

Nutritional StatusAdultBeveragesChildCohort StudiesDatabases, FactualDietEnergy IntakeFemaleFood, FortifiedHumansIndiaLinear ModelsMaleMeatPregnancyVitamin B 12Vitamin B ComplexSource

Identifiers

PMID24866058
PMCPMC4266598
OpenAlexW2154341767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.