SynthesisEuropean radiology2014
The value of diffusion-weighted imaging in the detection of prostate cancer: a meta-analysis.
Synthesis in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Small Study Effects in Diagnostic Imaging Accuracy: A Meta-Analysis.JAMA network open · 2022Pooled it
- The diagnostic accuracy of high b-value diffusion- and TAbdominal radiology (New York) · 2018Pooled it
- Empirical noise mapping guides optimal region-of-interest selection for accurate noise estimation in prostate DWI.Journal of applied clinical medical physics · 2026Article
- Artificial intelligence-generated apparent diffusion coefficient (AI-ADC) maps for prostate gland assessment: a multi-reader study.European radiology · 2026Article
- Application of high-density 2D receiver coil arrays for improved SNR in prostate MRI.Magnetic resonance in medicine · 2025Article
- Comparison of diagnostic performance between diffusion models parameters and mono-exponential apparent diffusion coefficient in patients with prostate cancer: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Review
- Up-to-Date Imaging and Diagnostic Techniques for Prostate Cancer: A Literature Review.Diagnostics (Basel, Switzerland) · 2023Review
- Reduced field-of-view and multi-shot DWI acquisition techniques: Prospective evaluation of image quality and distortion reduction in prostate cancer imaging.Magnetic resonance imaging · 2022Article
- Comparison of single-shot EPI and multi-shot EPI in prostate DWI at 3.0 T.Scientific reports · 2022Article
- Diffusion-weighted imaging in prostate cancer.Magma (New York, N.Y.) · 2022Review
- [Multiparametric MRI of the prostate].Der Urologe. Ausg. A · 2022Article
- Article
- The utility of ADC parameters in the diagnosis of clinically significant prostate cancer by 3.0-Tesla diffusion-weighted magnetic resonance imaging.Polish journal of radiology · 2021Article
- A Fully Automatic Artificial Intelligence System Able to Detect and Characterize Prostate Cancer Using Multiparametric MRI: Multicenter and Multi-Scanner Validation.Frontiers in oncology · 2021Article
- Rectal gas-induced susceptibility artefacts on prostate diffusion-weighted MRI with epi read-out at 3.0 T: does a preparatory micro-enema improve image quality?Abdominal radiology (New York) · 2020Article
- Comparative Study of Monoexponential, Intravoxel Incoherent Motion, Kurtosis, and IVIM-Kurtosis Models for the Diagnosis and Aggressiveness Assessment of Prostate Cancer.Frontiers in oncology · 2020Article
- Biomarkers That Differentiate Benign Prostatic Hyperplasia from Prostate Cancer: A Literature Review.Cancer management and research · 2020Review
- The impact of MRI sequence on tumour staging and gross tumour volume delineation in squamous cell carcinoma of the anal canal.European radiology · 2018Article
- Validation of the Dominant Sequence Paradigm and Role of Dynamic Contrast-enhanced Imaging in PI-RADS Version 2.Radiology · 2017Article
- [Multiparametric MRI of the prostate : Important radiological findings for urologists].Der Radiologe · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the diagnostic performance of diffusion-weighted imaging (DWI) as a single non-invasive method in detecting prostate cancer (PCa) and to deduce its clinical utility.
methodsA systematic literature search was performed to identify relevant original studies. Quality of included studies was assessed by QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies). Data were extracted to calculate sensitivity and specificity as well as running the test of heterogeneity and threshold effect. The summary receiver operating characteristic (SROC) curve was drawn and area under SROC curve (AUC) served as a determination of the diagnostic performance of DWI for the detection of PCa.
resultsA total of 21 studies were included, with 27 subsets of data available for analysis. The pooled sensitivity and specificity with corresponding 95% confidence interval (CI) were 0.62 (95% CI 0.61-0.64) and 0.90 (95% CI 0.89-0.90), respectively. Pooled positive likelihood ratio and negative likelihood ratio were 5.83 (95% CI 4.61-7.37) and 0.30 (95% CI 0.23-0.39), respectively. The AUC was 0.8991. Significant heterogeneity was observed. There was no notable publication bias.
conclusionsDWI is an informative MRI modality in detecting PCa and shows moderately high diagnostic accuracy. General clinical application was limited because of the absence of standardized DW-MRI techniques. KEY POINTS: • DWI provides incremental information for the detection and evaluation of PCa • DWI has moderately high diagnostic accuracy in detecting PCa • Patient condition, imaging protocols and study design positively influence diagnostic performance • General clinical application requires optimization of image acquisition and interpretation.
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