Evidence map›Paper›PMID 24865688›Full record

ArticleThe American journal of tropical medicine and hygiene2014

Prevalence of human-active and variant 1 strains of the tick-borne pathogen Anaplasma phagocytophilum in hosts and forests of eastern North America.

Felicia Keesing, Diana J McHenry, Michelle Hersh, Michael Tibbetts, Jesse L Brunner, Mary Killilea, Kathleen LoGiudice, Kenneth A Schmidt, Richard S Ostfeld

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Ecological relationships ofParasitology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Detection of multiple tick-borne pathogens inCurrent research in parasitology & vector-borne diseases · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Felicia KeesingBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York keesing@bard.edu.
Diana J McHenryBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Michelle HershBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Michael TibbettsBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Jesse L BrunnerBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Mary KillileaBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Kathleen LoGiudiceBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Kenneth A SchmidtBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
Richard S OstfeldBard College, Annandale-on-Hudson, New York; Sarah Lawrence College, Bronxville, New York; Washington State University, Pullman, Washington; New York University, New York, New York; Union College, Schenectady, New York; Texas Tech University, Lubbock, Texas; Cary Institute of Ecosystem Studies, Millbrook, New York.
New York University · USSarah Lawrence College · USUnion College · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplasmosis is an emerging infectious disease caused by infection with the bacterium Anaplasma phagocytophilum. In the eastern United States, A. phagocytophilum is transmitted to hosts through the bite of the blacklegged tick, Ixodes scapularis. We determined the realized reservoir competence of 14 species of common vertebrate hosts for ticks by establishing the probability that each species transmits two important strains of A. phagocytophilum (A. phagocytophilum human-active, which causes human cases, and A. phagocytophilum variant 1, which does not) to feeding larval ticks. We also sampled questing nymphal ticks from ∼ 150 sites in a single county over 2 years and sampled over 6 years at one location. White-footed mice (Peromyscus leucopus) and Eastern chipmunks (Tamias striatus) were the most competent reservoirs for infection with the A. phagocytophilum human-active strain. Across the county, prevalence in ticks for both strains together was 8.3%; ticks were more than two times as likely to be infected with A. phagocytophilum human-active as A. phagocytophilum variant 1.

Indexed as

Rodent DiseasesAnaplasma phagocytophilumAnaplasmosisAnimalsBacterial Outer Membrane ProteinsDisease ReservoirsHumansIxodesLarvaNorth AmericaNymphPeromyscusPrevalenceRodentiaSciuridaeTreesBacterial Outer Membrane Proteinsmsp2 protein, Anaplasma phagocytophilum

Identifiers

PMID24865688
PMCPMC4125253
OpenAlexW2319921832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.