ReviewPediatric nephrology (Berlin, Germany)2015
Acute and chronic antibody-mediated rejection in pediatric kidney transplantation.
Review in Pediatric nephrology (Berlin, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Exploratory Screening and Replication of Urinary Biomarkers of Fruit and Vegetable Intake in Free-living European Children and Adolescents Using Untargeted Metabolomics.The Journal of nutrition · 2026Article
- Cellular and Molecular Aspects of Chronic Rejection.Results and problems in cell differentiation · 2026Review
- The Impact of Non-Donor-Specific HLA Antibodies on Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients.International journal of molecular sciences · 2025Article
- Understanding Pediatric Kidney Transplant Rejection: Its Pathophysiology, Biomarkers, and Management Strategies.Current medicinal chemistry · 2025Review
- Positive B cell flow cytometry crossmatch without detectable donor-specific antibodies: true or false reactivity?Frontiers in immunology · 2025Article
- Development of Non-HLA Antibodies and Their Association With Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Antibody-mediated rejection in pediatric kidney transplant recipients: A report from the Pediatric Nephrology Research Consortium.Pediatric transplantation · 2024Review
- Rejection markers in kidney transplantation: do new technologies help children?Pediatric nephrology (Berlin, Germany) · 2023Review
- Therapeutic apheresis in kidney diseases: an updated review.Renal failure · 2022Review
- Role of therapeutic apheresis in the treatment of pediatric kidney diseases.Pediatric nephrology (Berlin, Germany) · 2022Article
- Cytokine Profiles in Children After Pediatric Kidney Transplantation With Acute Cellular Compared to Chronic Antibody-mediated Rejection and Stable Patients: A Pilot Study.Transplantation direct · 2019Article
- Persistent C4d and antibody-mediated rejection in pediatric renal transplant patients.Pediatric transplantation · 2017Article
- Challenges in pediatric renal transplantation.World journal of transplantation · 2014Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute antibody-mediated rejection is a diagnostic challenge in renal transplantation medicine. However, it is an important diagnosis to make, since chronic antibody-mediated rejection (CAMR) is the main cause of long-term graft loss. Antibody-mediated rejection is diagnosed by detecting donor-specific antibodies (DSAs) in the blood in combination with observing typical histomorphological signs in kidney biopsy, as described in the Banff classification. Therapy is based on the removal of DSAs by administering intravenous immunoglobulins (IVIGs), plasmapheresis, or immunoadsorption. Reoccurrence of antibodies is diminished by the use of rituximab, increased immunosuppression, and in some cases additional experimental substances. A combination of these techniques has been shown to be successful in the majority of cases of acute and chronic antibody-mediated rejection. Routine DSA monitoring is warranted for early detection of antibody-mediated rejection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.