Evidence map›Paper›PMID 24865127›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2014

Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample.

Argyris Stringaris, Natalie Castellanos-Ryan, Tobias Banaschewski, Gareth J Barker, Arun L Bokde, Uli Bromberg, Christian Büchel, Mira Fauth-Bühler, Herta Flor, Vincent Frouin and 16 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 14 institutions in 6 countries.

Argyris StringarisInstitute of Psychiatry, King's College London, London, UK.
Natalie Castellanos-Ryan
Tobias Banaschewski
Gareth J Barker
Arun L Bokde
Uli Bromberg
Christian Büchel
Mira Fauth-Bühler
Herta Flor
Vincent Frouin
Juergen Gallinat
Hugh Garavan
Penny Gowland
Andreas Heinz
Bernd Itterman
Claire Lawrence
Frauke Nees
Marie-Laure Paillere-Martinot
Tomas Paus
Zdenka Pausova
Marcella Rietschel
Michael N Smolka
Gunter Schumann
Robert Goodman
Patricia Conrod
Imagen Consortium
King's College London · GBCentral Institute of Mental Health · DECharité - Universitätsmedizin Berlin · DECommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRTrinity College Dublin · IEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Nottingham · GBCentre Hospitalier Universitaire Sainte-Justine · CAHeidelberg University · DEMcGill University · CAPhysikalisch-Technische Bundesanstalt · DETU Dresden · DEUniversity Hospital Heidelberg · DEUniversity of Toronto · CA

Funding

Medical Research Council G0901858Wellcome Trust 093909
6 · The paper itself

Abstract

backgroundIt has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation of high energy and cheerfulness is associated with superior cognitive performance.

methodWe studied 1755 participants of the IMAGEN study, of average age 14.4 years (SD = 0.43), 50.7% girls. Manic symptoms were assessed using the Development and Wellbeing Assessment by interviewing parents and young people. Cognition was assessed using the Wechsler Intelligence Scale For Children (WISC-IV) and a response inhibition task.

resultsManic symptoms in youth formed two correlated dimensions: one termed exuberance, characterized by high energy and cheerfulness and one of undercontrol with distractibility, irritability and risk-taking behavior. Only the undercontrol, but not the exuberant dimension, was independently associated with measures of psychosocial impairment. In multivariate regression models, the exuberant, but not the undercontrolled, dimension was positively and significantly associated with verbal IQ by both parent- and self-report; conversely, the undercontrolled, but not the exuberant, dimension was associated with poor performance in a response inhibition task.

conclusionsOur findings suggest that manic symptoms in youth may form dimensions with distinct correlates. The results are in keeping with previous findings about superior performance associated with mania. Further research is required to study etiological differences between these symptom dimensions and their implications for clinical practice.

Indexed as

Inhibition, PsychologicalAdolescentBipolar DisorderFemaleHumansIntelligenceMalePsychomotor PerformanceadolescentsbipolarcreativityintelligenceMania

Identifiers

PMID24865127
PMCPMC4167034
OpenAlexW2074187760

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.