Evidence map›Paper›PMID 24864199›Full record

Trial reportJournal of obesity2014

Lifestyle intervention involving calorie restriction with or without aerobic exercise training improves liver fat in adults with visceral adiposity.

Eiichi Yoshimura, Hideaki Kumahara, Takuro Tobina, Takuro Matsuda, Makoto Ayabe, Akira Kiyonaga, Keizo Anzai, Yasuki Higaki, Hiroaki Tanaka

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of obesity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 10 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 10 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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  14. Comprehensive lifestyle interventionWorld journal of gastroenterology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Eiichi YoshimuraFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan ; Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3-1-100 Tsukide, Higashi-ku, Kumamoto 862-8502, Japan.ORCID 0000-0002-7517-7260
Hideaki KumaharaFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan ; Faculty of Nutritional Sciences, Nakamura Gakuen University, 5-7-1 Befu, Jonan-ku, Fukuoka 814-0104, Japan.
Takuro TobinaFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan ; Faculty of Nursing and Nutrition, Nagasaki University, 1-1-1 Manabino, Nagayo, Nishisonogi-gun, Nagasaki 851-2195, Japan.ORCID 0000-0003-4789-2563
Takuro MatsudaFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Makoto AyabeFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan ; Faculty of Computer Science and Systems Engineering, Okayama Prefectural University, 111 Kuboki, Soja-shi, Okayama 719-1197, Japan.
Akira KiyonagaFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.ORCID 0000-0002-7468-3671
Keizo AnzaiDepartment of Internal Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.
Yasuki HigakiFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Hiroaki TanakaFaculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan ; Institute for Physical Activity, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
Fukuoka University · JPOkayama Prefectural University · JPPrefectural University of Kumamoto · JPSaga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of calorie restriction-induced weight loss with or without aerobic exercise on liver fat.

methodsThirty-three adults with visceral adiposity were divided into calorie restriction (CR; n = 18) or CR and aerobic exercise (CR + Ex; n = 15) groups. Target energy intake was 25 kcal/kg of ideal body weight. The CR + Ex group had a targeted exercise time of 300 min/wk or more at lactate threshold intensity for 12 weeks.

resultsReductions in body weight (CR, -5.3 ± 0.8 kg; CR + Ex, -5.1 ± 0.7 kg), fat mass (CR, -4.9 ± 0.9 kg; CR + Ex, -4.4 ± 0.6 kg), and visceral fat (CR, -24 ± 5 cm2; CR + Ex, -37 ± 5 cm2) were not statistically different between groups. Liver fat decreased significantly in both groups, with no difference between groups. Change in maximal oxygen uptake was significantly greater in the CR + Ex group than in the CR group (CR, -0.7 ± 0.7 mL/kg/min; CR + Ex, 2.9 ± 1.0 mL/kg/min).

conclusionBoth CR and CR + Ex resulted in an improved reduction in liver fat; however, there was no additive effect of exercise training.

Indexed as

AdiposityCaloric RestrictionNon-alcoholic Fatty Liver DiseaseWeight LossAdultExerciseFemaleHumansIntra-Abdominal FatLife StyleLiverMaleMiddle AgedObesity, AbdominalOverweightOxygen Consumption

Identifiers

PMID24864199
PMCPMC4016916
OpenAlexW2166643986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.