Evidence map›Paper›PMID 24864170›Full record

ArticlePediatrics2014

Safety and efficacy of filtered sunlight in treatment of jaundice in African neonates.

Tina M Slusher, Hendrik J Vreman, Bolajoko O Olusanya, Ronald J Wong, Ann M Brearley, Yvonne E Vaucher, David K Stevenson

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Care-seeking behavior for neonatal jaundice in rural northern Nigeria.Public health in practice (Oxford, England) · 2020
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Review
  16. Observational
  17. Sister Jean Ward, phototherapy, and jaundice: a unique human and photochemical interaction.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Tina M Slusher
Hendrik J Vreman
Bolajoko O Olusanya
Ronald J Wong
Ann M Brearley
Yvonne E Vaucher
David K Stevenson
Stanford University · USUniversity of Minnesota · USCentre for Healthy Start Initiative · NGUniversity of California, San Diego · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
NICHD Coooperative Multicenter Neonatal Research NetworkU10HD040461 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VAUCHER, YVONNE ELEANOR · 2001 to 2015
$2.8M
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1TR000114NICHD NIH HHS U10 HD040461
6 · The paper itself

Abstract

objectivesEvaluate safety and efficacy of filtered-sunlight phototherapy (FS-PT).

methodsTerm/late preterm infants #14 days old with clinically significant jaundice, assessed by total bilirubin (TB) levels, were recruited from a maternity hospital in Lagos, Nigeria. Sunlight was filtered with commercial window-tinting films that remove most UV and significant levels of infrared light and transmit effective levels of therapeutic blue light. After placing infants under an FS-PT canopy, hourly measurements of axillary temperatures, monitoring for sunburn, dehydration, and irradiances of filtered sunlight were performed. Treatment was deemed safe and efficacious if infants were able to stay in FS-PT for $5 hours and rate of rise of TB was ,0.2 mg/dL/h for infants #72 hours of age or TB decreased for infants .72 hours of age.

resultsA total of 227 infants received 258 days of FS-PT. No infant developed sunburn or dehydration. On 85 (33%) of 258 treatment days, infants were removed briefly from FS-PT due to minor temperature-related adverse events. No infant met study exit criteria. FS-PT was efficacious in 92% (181/197) of evaluable treatment days. Mean 6 SD TB change was –0.06 6 0.19 mg/dL/h. The mean 6 SD (range) irradiance of FS-PT was 38 6 22 (2–115) mW/cm2/nm, measured by the BiliBlanket Meter II.

conclusionsWith appropriate monitoring, filtered sunlight is a novel, practical, and inexpensive method of PT that potentially offers safe and efficacious treatment strategy for management of neonatal jaundice in tropical countries where conventional PT treatment is not available.

Indexed as

Black or African AmericanDeveloping CountriesBilirubinBody TemperatureFemaleFiltrationHeliotherapyHospitals, MaternityHumansInfant, NewbornInfant, Premature, DiseasesJaundice, NeonatalMaleNigeriaTreatment OutcomeBilirubin

Identifiers

PMID24864170
PMCPMC4531268
OpenAlexW2076301358

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.