ReviewEuropean heart journal2014
Importance of frailty in patients with cardiovascular disease.
Review in European heart journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 123 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Trial to Evaluate the Utility of Focused Frailty Interventions on Patients Undergoing Evaluation for Left Ventricular Assist Device (LVAD) Placement
Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.
A Prospective Trial to Evaluate the Utility of Focused Frailty Interventions on Patients With Advanced Heart Failure
Assessment of Frailty in Elderly Patients Undergoing Elective Cardiac Surgery
Effects of High Intensity Resistance Training on Physical Function in Possible Sarcopenia Cases
Who cites it
123 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between frailty and adverse outcomes after cardiac resynchronization therapy: a systematic review and meta-analysis.European geriatric medicine · 2025Pooled it
- Physical functional performance and prognosis in patients with heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2020Pooled it
- Effects of Acute Phase Intensive Electrical Muscle Stimulation in Frail Elderly Patients With Acute Heart Failure (ACTIVE-EMS): Rationale and protocol for a multicenter randomized controlled trial.Clinical cardiology · 2017Trial
- Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial.BMJ (Clinical research ed.) · 2016Trial
- Impact of Nutritional Risk on Long-Term Prognosis in Older Patients With Stage B Heart Failure: A PAPRIKA-HF Registry Subanalysis.Circulation reports · 2026Article
- Beyond Chronological Age: Frailty, Vulnerability, and Invasive Decision-Making in Older Adults with Acute Coronary Syndromes.Geriatrics (Basel, Switzerland) · 2026Review
- Article
- Temporal therapeutic mismatch in frail older adults with heart Failure: A framework for Frailty-Informed prescribing.International journal of cardiology. Heart & vasculature · 2026Review
- Frailty as a predictor of adverse in-hospital outcomes in older patients with Takotsubo cardiomyopathy.Journal of geriatric cardiology : JGC · 2026Article
- Region-specific vulnerability to vascular risk factors and modifiable protective influences on white matter hyperintensities.Communications medicine · 2026Article
- Increased all-cause mortality following distal radius fractures in Danish adults: a register-based matched cohort study.Acta orthopaedica · 2026Article
- Screening for Pre-Frailty Using Phase Angle Derived from Bioelectrical Impedance Analysis in Community-Dwelling Older Adults.Geriatrics (Basel, Switzerland) · 2026Article
- Bidirectional association between asthma and cardiovascular disease in middle-aged and older Chinese adults: the mediating effect of frailty.Journal of health, population, and nutrition · 2026Article
- Platelet hyperreactivity and frailty in a mouse model of Alzheimer's disease are prevented by anti-oxidant treatment.GeroScience · 2026Article
- Frailty Modifies the Prognostic Effect of Age Among Older Adults With Acute Coronary Syndrome.Journal of the American Heart Association · 2026Observational
- Association between frailty and cognitive impairment in elderly patients with acute cerebral infarction.Frontiers in aging neuroscience · 2026Article
- Cardiac Rehabilitation and Cardiovascular Prevention in Patients with Type 2 Diabetes Mellitus: From Initial Assessment to Comprehensive Management.Journal of clinical medicine · 2025Review
- Cardiac Rehabilitation and Heart Failure With Preserved Ejection Fraction.Circulation reports · 2025Article
- Frailty Risk After a Cardiovascular Event Among Community-Dwelling Older People: Influence of Sociodemographic, Polypharmacy, and Pre-event Frailty.The Canadian journal of cardiology · 2025Article
- Article
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality. With the ageing population, the prognostic determinants among others include frailty, health status, disability, and cognition. These constructs are seldom measured and factored into clinical decision-making or evaluation of the prognosis of these at-risk older adults, especially as it relates to high-risk interventions. Addressing this need effectively requires increased awareness and their recognition by the treating cardiologists, their incorporation into risk prediction models when treating an elderly patient with underlying complex CVD, and timely referral for comprehensive geriatric management. Simple measures such as gait speed, the Fried score, or the Rockwood Clinical Frailty Scale can be used to assess frailty as part of routine care of elderly patients with CVD. This review examines the prevalence and outcomes associated with frailty with special emphasis in patients with CVD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.