Evidence map›Paper›PMID 24864076›Full record

ArticleThe Veterinary record2014

Association between the level of antibodies in bulk tank milk and bovine respiratory syncytial virus exposure in the herd.

T B Klem, T Tollersrud, O Osterås, M Stokstad

Abstract read
In one paragraph

Article in The Veterinary record, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

T B KlemDepartment of Production Animal Clinical Sciences, Norwegian University of Life Sciences, P.O. Box 8146 Dep., Oslo NO-0033, Norway.
T TollersrudNorwegian Veterinary Institute, P.O. Box 750 Sentrum, Oslo NO-0106, Norway.
O OsteråsDepartment of Cattle Health Services, TINE Norwegian Dairies, P.O. Box 58, Oslo NO-1431 Ås, Norway.
M StokstadDepartment of Production Animal Clinical Sciences, Norwegian University of Life Sciences, P.O. Box 8146 Dep., Oslo NO-0033, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody levels in bulk tank milk (BTM) against bovine respiratory syncytial virus (BRSV) are used to classify BRSV status of herds. The aim of this study was to investigate how these levels correspond with the time at which the herds were infected. Bulk tank milk, individual milk and serum samples from cows and young stock were investigated using an indirect ELISA. Screenings of BTM from 89 dairy herds during two winter seasons revealed a prevalence of positive herds from 82 per cent to 85 per cent. Eleven herds showed a marked increase in antibody levels between two screenings, indicating new infection. However, two of these herds had been free from BRSV for the last five to seven years. Two newly infected herds were monitored for four years and did not appear to get reinfected. Surprisingly, the BTM antibody levels in these herds remained high throughout the study period, but fluctuated significantly. This shows that the levels of antibodies in BTM can remain high for several years, even in herds where reinfection does not occur. BTM serology is a useful tool in the monitoring of infectious diseases in dairy herds, but has limitations as a diagnostic tool for BRSV infections.

Indexed as

AnimalsAntibodies, ViralCattleCattle DiseasesEnzyme-Linked Immunosorbent AssayFemaleMilkPopulation SurveillanceRespiratory Syncytial Virus, BovineRespiratory Syncytial Virus InfectionsAntibodies, Viral

Identifiers

PMID24864076
PMCPMC4112425

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.