ArticleThe European journal of neuroscience2014
Distinguishing informational from value-related encoding of rewarding and punishing outcomes in the human brain.
Article in The European journal of neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Trial
- Distinct Reward Properties are Encoded via Corticostriatal Interactions.Scientific reports · 2016Trial
- Representations of the intrinsic value of information in mouse orbitofrontal cortex.Nature neuroscience · 2026Article
- Ventrolateral orbital cortex as a functional hub in chronic pain and comorbid depression.Frontiers in neuroscience · 2026Article
- Reward and loss incentives improve spatial working memory by shaping trial-by-trial posterior frontoparietal signals.NeuroImage · 2022Article
- Independent and interacting value systems for reward and information in the human brain.eLife · 2022Article
- A Riemannian Geometry Theory of Synergy Selection for Visually-Guided Movement.Vision (Basel, Switzerland) · 2021Article
- Framing and self-responsibility modulate brain activities in decision escalation.BMC neuroscience · 2021Article
- Dissociable Neural Responses to Monetary and Social Gain and Loss in Women With Major Depressive Disorder.Frontiers in behavioral neuroscience · 2019Article
- Valuation of knowledge and ignorance in mesolimbic reward circuitry.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- 'Proactive' use of cue-context congruence for building reinforcement learning's reward function.BMC neuroscience · 2016Article
- Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage.Neurology · 2016Article
- Contextual modulation of value signals in reward and punishment learning.Nature communications · 2015Article
- Impulsive traits and unplanned suicide attempts predict exaggerated prefrontal response to angry faces in the elderly.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Article
- Prioritising the relevant information for learning and decision making within orbital and ventromedial prefrontal cortex.Current opinion in behavioral sciences · 2015Article
- Transcranial Direct Current Stimulation over the Medial Prefrontal Cortex and Left Primary Motor Cortex (mPFC-lPMC) Affects Subjective Beauty but Not Ugliness.Frontiers in human neuroscience · 2015Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
There is accumulating evidence implicating a set of key brain regions in encoding rewarding and punishing outcomes, including the orbitofrontal cortex, medial prefrontal cortex, ventral striatum, anterior insula, and anterior cingulate. However, it has proved challenging to reach consensus concerning the extent to which different brain areas are involved in differentially encoding rewarding and punishing outcomes. Here, we show that many of the brain areas involved in outcome processing represent multiple outcome components: encoding the value of outcomes (whether rewarding or punishing) and informational coding, i.e. signaling whether a given outcome is rewarding or punishing, ignoring magnitude or experienced utility. In particular, we report informational signals in the lateral orbitofrontal cortex and anterior insular cortex that respond to both rewarding and punishing feedback, even though value-related signals in these areas appear to be selectively driven by punishing feedback. These findings highlight the importance of taking into account features of outcomes other than value when characterising the contributions of different brain regions in outcome processing.
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Registered trials
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