Evidence map›Paper›PMID 24862963›Full record

ArticleThe British journal of surgery2014

Cost-effectiveness of the National Health Service Abdominal Aortic Aneurysm Screening Programme in England.

M J Glover, L G Kim, M J Sweeting, S G Thompson, M J Buxton

Abstract read
In one paragraph

Article in The British journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Recommendations on screening for abdominal aortic aneurysm in primary care.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Guideline
  2. Pooled it
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  10. One-time screening for abdominal aortic aneurysm in Ontario, Canada: a model-based cost-utility analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M J GloverHealth Economics Research Group, Brunel University, London, UK.
L G Kim
M J Sweeting
S G Thompson
M J Buxton

Funding

British Heart Foundation RG/08/014/24067Department of Health 08/30/02Medical Research Council MR/L003120/1
6 · The paper itself

Abstract

backgroundImplementation of the National Health Service abdominal aortic aneurysm (AAA) screening programme (NAAASP) for men aged 65 years began in England in 2009. An important element of the evidence base supporting its introduction was the economic modelling of the long-term cost-effectiveness of screening, which was based mainly on 4-year follow-up data from the Multicentre Aneurysm Screening Study (MASS) randomized trial. Concern has been expressed about whether this conclusion of cost-effectiveness still holds, given the early performance parameters, particularly the lower prevalence of AAA observed in NAAASP.

methodsThe existing published model was adjusted and updated to reflect the current best evidence. It was recalibrated to mirror the 10-year follow-up data from MASS; the main cost parameters were re-estimated to reflect current practice; and more robust estimates of AAA growth and rupture rates from recent meta-analyses were incorporated, as were key parameters as observed in NAAASP (attendance rates, AAA prevalence and size distributions).

resultsThe revised and updated model produced estimates of the long-term incremental cost-effectiveness of £5758 (95 per cent confidence interval £4285 to £7410) per life-year gained, or £7370 (£5467 to £9443) per quality-adjusted life-year (QALY) gained.

conclusionAlthough the updated parameters, particularly the increased costs and lower AAA prevalence, have increased the cost per QALY, the latest modelling provides evidence that AAA screening as now being implemented in England is still highly cost-effective.

Indexed as

Aortic Aneurysm, AbdominalAortic RuptureCost-Benefit AnalysisEarly DiagnosisEnglandHumansMaleMass ScreeningModels, EconomicQuality-Adjusted Life YearsState MedicineUltrasonography

Identifiers

PMID24862963
PMCPMC4231222

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.