ReviewExperimental dermatology2014
Merkel cells and touch domes: more than mechanosensory functions?
Review in Experimental dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers.Nature communications · 2026Article
- Integrated Sensory and Immune Cell Organization in the Lip Skin of the Goldfish (Animals : an open access journal from MDPI · 2026Article
- Choline acetyltransferase as a marker for Merkel cells in mucosal and skin tissues.Journal of oral biosciences · 2026Article
- An innovative in vitro system unveils IGF1R signaling regulating Merkel cell generation.Stem cell reports · 2026Article
- Article
- A Taxonomy of Pressure Sensors for Compression Garment Development.Sensors (Basel, Switzerland) · 2025Review
- Development and regeneration of Merkel cells.Current topics in developmental biology · 2025Review
- POU4F3 Is Necessary for Normal Merkel Cell Formation, whereas POU4F1 Is Dispensable.The Journal of investigative dermatology · 2025Article
- Different expression patterns of p63 and p73 in Felis catus papillomavirus type 2-associated feline Merkel cell carcinomas and other epidermal carcinomas.The Journal of veterinary medical science · 2024Article
- A helping hand: roles for accessory cells in the sense of touch across species.Frontiers in cellular neuroscience · 2024Review
- Neurophysiology, Neuro-Immune Interactions, and Mechanobiology in Osteopathy in the Cranial Field: An Evidence-Informed Perspective for a Scientific Rationale.Healthcare (Basel, Switzerland) · 2023Article
- Merkel-like basal cells in the nasal septal island of dromedaries: Ultrastructure and possible functions.Saudi journal of biological sciences · 2023Article
- Merkel Cell Polyomavirus: Infection, Genome, Transcripts and Its Role in Development of Merkel Cell Carcinoma.Cancers · 2023Review
- [Research advances on the function of skin touch receptor Merkel cells].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Human fetal skin derived merkel cells display distinctive characteristicsFrontiers in bioengineering and biotechnology · 2022Article
- LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers.Virchows Archiv : an international journal of pathology · 2021Article
- Somatosensory innervation of healthy human oral tissues.The Journal of comparative neurology · 2021Article
- The Fungiform Papilla Is a Complex, Multimodal, Oral Sensory Organ.Current opinion in physiology · 2021Article
- Reciprocal signals between nerve and epithelium: how do neurons talk with epithelial cells?American journal of stem cells · 2021Review
- Shedding Light on the Effects of Calorie Restriction and its Mimetics on Skin Biology.Nutrients · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The touch dome (TD) is an innervated structure in the epidermis of mammalian skin. Composed of specialized keratinocytes and neuroendocrine Merkel cells, the TD has distinct molecular characteristics compared to the surrounding epidermal keratinocytes. Much of the research on Merkel cell function has focused on their role in mechanosensation, specifically light touch. Recently, more has been discovered about Merkel cell molecular characteristics and their cells of origin. Here we review Merkel cell and TD biology, and discuss potential functions beyond mechanosensation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.