ArticleAdvanced healthcare materials2014
Biphasic ferrogels for triggered drug and cell delivery.
Article in Advanced healthcare materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- 3D Printing of Magnetic Soft Materials for Functional Structures and Devices.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Article
- 4D-Printed Magnetic Responsive Bilayer Hydrogel.Nanomaterials (Basel, Switzerland) · 2025Article
- Mechanoresponsive Drug Release from a Flexible, Tissue-Adherent, Hybrid Hydrogel Actuator.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Bioinspired Stimuli-Responsive Materials for Soft Actuators.Biomimetics (Basel, Switzerland) · 2024Review
- Nanocomposite Hydrogels as Functional Extracellular Matrices.Gels (Basel, Switzerland) · 2023Review
- Emerging Magnetic Fabrication Technologies Provide Controllable Hierarchically-Structured Biomaterials and Stimulus Response for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Functional Thermoresponsive Hydrogel Molecule to Material Design for Biomedical Applications.Polymers · 2022Review
- Magnetic Soft Materials and Robots.Chemical reviews · 2022Review
- Programmable Mechanically Active Hydrogel-Based Materials.Advanced materials (Deerfield Beach, Fla.) · 2021Review
- Magnetic systems for cancer immunotherapy.Acta pharmaceutica Sinica. B · 2021Review
- Silk reservoir implants for sustained drug delivery.ACS applied bio materials · 2021Article
- Magnetic microgels and nanogels: Physical mechanisms and biomedical applications.Bioengineering & translational medicine · 2021Review
- Active biomaterials for mechanobiology.Biomaterials · 2021Review
- Multifunctional magnetic soft composites: a review.Multifunctional materials · 2020Article
- Bisphosphonate-based nanocomposite hydrogels for biomedical applications.Bioactive materials · 2020Review
- Use of nanoparticles in skeletal tissue regeneration and engineering.Histology and histopathology · 2020Review
- Smart Hydrogels in Tissue Engineering and Regenerative Medicine.Materials (Basel, Switzerland) · 2019Review
- Advances in immunotherapy delivery from implantable and injectable biomaterials.Acta biomaterialia · 2019Review
- Ultrasonic Generation of Pulsatile and Sequential Therapeutic Delivery Profiles from Calcium-Crosslinked Alginate Hydrogels.Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Ferrogels are an attractive material for many biomedical applications due to their ability to deliver a wide variety of therapeutic drugs on-demand. However, typical ferrogels have yet to be optimized for use in cell-based therapies, as they possess limited ability to harbor and release viable cells. Previously, an active porous scaffold that exhibits large deformations and enhanced biological agent release under moderate magnetic fields has been demonstrated. Unfortunately, at small device sizes optimal for implantation (e.g., 2 mm thickness), these monophasic ferrogels no longer achieve significant deformation due to a reduced body force. A new biphasic ferrogel, containing an iron oxide gradient, capable of large deformations and triggered release even at small gel dimensions, is presented in this study. Biphasic ferrogels demonstrate increased porosity, enhanced mechanical properties, and potentially increased biocompatibility due to their reduced iron oxide content. With their ability to deliver drugs and cells on-demand, it is expected that these ferrogels will have wide utility in the fields of tissue engineering and regenerative medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.