ArticleInternational journal of surgery case reports2014
Renal cell carcinoma metastasis to the parathyroid gland: A very rare occurrence.
Article in International journal of surgery case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Metastases to the Parathyroid Glands: A Comprehensive Literature Review of 127 Reported Cases.Head and neck pathology · 2018Review
- Metastasis of renal cell carcinoma to the parathyroid gland 16 years after radical nephrectomy: A case report.Oncology letters · 2016Article
- Unexpected rare metastases of renal cell carcinoma.World journal of nuclear medicineArticle
- PARATHYROID CARCINOMA WITH LACK OF CLINICAL SYMPTOMS: A CASE REPORT AND REVIEW OF LITERATURE.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMetastases to the parathyroid gland are very uncommon. Although renal cell carcinoma metastasis to the head and neck region is well recognised, with a predilection for unpredictable metastasis to unusual sites such as the thyroid gland, nose, paranasal sinuses, and cranial bones, there are no reports of parathyroid gland involvement. PRESENTATION OF CASE: We describe an unusual case of renal cell carcinoma metastasis to a parathyroid gland in a 69-year-old male who had been treated 8 years previously for a pT3b N0 M1 clear cell carcinoma of the right kidney with a right nephrectomy, and interferon immunotherapy for 18 months. The patient had originally presented to the plastic surgeons with a rapidly enlarging 3cm superficial lesion on the ventral aspect of the left forearm, which was excised with histology revealing metastatic renal (clear) cell carcinoma. DISCUSSION: Renal cell carcinoma has a reputation for unpredictable patterns of metastasis, and our case highlights this, with the first description in the literature of parathyroid gland metastasis. Despite the poor prognosis associated with metastatic renal cell carcinoma, our patient is still alive 10 years following original presentation, despite having metastasis to two different extra-renal sites and a shortened course of initial adjuvant systemic therapy.
conclusionIn parathyroid gland metastasis, metastectomy can offer excellent local long term local control.
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