ArticleInternational journal of cancer2015
Lung cancer risk among bricklayers in a pooled analysis of case-control studies.
Article in International journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Absence of multiplicative interactions between occupational lung carcinogens and tobacco smoking: a systematic review involving asbestos, crystalline silica and diesel engine exhaust emissions.BMC public health · 2017Pooled it
- Lung Cancer Risks Associated with Occupational Exposure to Pairs of Five Lung Carcinogens: Results from a Pooled Analysis of Case-Control Studies (SYNERGY).Environmental health perspectives · 2024Article
- Pleural mesothelioma risk in the construction industry: a case-control study in Italy, 2000-2018.BMJ open · 2023Article
- Social determinants of health among family caregiver centered outcomes in lung cancer: a systematic review.Journal of thoracic disease · 2023Review
- Lung cancer risk in relation to jobs held in a nationwide case-control study in Iran.Occupational and environmental medicine · 2022Article
- Etiology of lung cancer: Evidence from epidemiologic studies.Journal of the National Cancer Center · 2022Review
- Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.Cancers · 2022Review
- Asbestos Exposure and Malignant Mesothelioma in Construction Workers-Epidemiological Remarks by the Italian National Mesothelioma Registry (ReNaM).International journal of environmental research and public health · 2021Article
- Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium.Occupational and environmental medicine · 2021Article
- Environmental and occupational determinants of lung cancer.Translational lung cancer research · 2019Review
- Evaluation of DNA Methylation Changes and Micronuclei in Workers Exposed to a Construction Environment.International journal of environmental research and public health · 2019Observational
- Micronucleus Assay in Exfoliated Buccal Epithelial Cells Using Liquid Based Cytology Preparations in Building Construction Workers.Iranian journal of pathology · 2018Article
- Characteristics, survival, and risk factors of Chinese young lung cancer patients: the experience from two institutions.Oncotarget · 2017Article
- Epidemiology in Germany-general development and personal experience.European journal of epidemiology · 2017Article
- Occupational exposure in the removal and disposal of asbestos-containing materials in Italy.International archives of occupational and environmental health · 2016Article
- Lung cancer risk among workers in the construction industry: results from two case-control studies in Montreal.BMC public health · 2015Article
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51 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bricklayers may be exposed to several lung carcinogens, including crystalline silica and asbestos. Previous studies that analyzed lung cancer risk among these workers had several study design limitations. We examined lung cancer risk among bricklayers within SYNERGY, a large international pooled analysis of case-control studies on lung cancer and the joint effects of occupational carcinogens. For men ever employed as bricklayers we estimated odds ratios (OR) and 95% confidence intervals (CI) adjusted for study center, age, lifetime smoking history and employment in occupations with exposures to known or suspected lung carcinogens. Among 15,608 cases and 18,531 controls, there were 695 cases and 469 controls who had ever worked as bricklayers (OR: 1.47; 95% CI: 1.28-1.68). In studies using population controls the OR was 1.55 (95% CI: 1.32-1.81, 540/349 cases/controls), while it was 1.24 (95% CI: 0.93-1.64, 155/120 cases/controls) in hospital-based studies. There was a clear positive trend with length of employment (p < 0.001). The relative risk was higher for squamous (OR: 1.68, 95% CI: 1.42-1.98, 309 cases) and small cell carcinomas (OR: 1.78, 95% CI: 1.44-2.20, 140 cases), than for adenocarcinoma (OR: 1.17, 95% CI: 0.95-1.43, 150 cases) (p-homogeneity: 0.0007). ORs were still elevated after additional adjustment for education and in analyses using blue collar workers as referents. This study provided robust evidence of increased lung cancer risk in bricklayers. Although non-causal explanations cannot be completely ruled out, the association is plausible in view of the potential for exposure to several carcinogens, notably crystalline silica and to a lesser extent asbestos.
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