Evidence map›Paper›PMID 24861961›Full record

ArticleHuman brain mapping2014

Atomic dynamic functional interaction patterns for characterization of ADHD.

Jinli Ou, Zhichao Lian, Li Xie, Xiang Li, Peng Wang, Yun Hao, Dajiang Zhu, Rongxin Jiang, Yufeng Wang, Yaowu Chen and 2 more

Abstract read
In one paragraph

Article in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Functional Neuroimaging in the New Era of Big Data.Genomics, proteomics & bioinformatics · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Large-Scale Circuitry Interactions Upon Earthquake Experiences Revealed by Recurrent Neural Networks.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2018
    Article
  13. Review
  14. Review
  15. Review
  16. Intrinsic Functional Connectivity in Attention-Deficit/Hyperactivity Disorder: A Science in Development.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2016
    Article
  17. Bayesian Inference for Functional Dynamics Exploring in fMRI Data.Computational and mathematical methods in medicine · 2016
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jinli OuSchool of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Zhichao Lian
Li Xie
Xiang Li
Peng Wang
Yun Hao
Dajiang Zhu
Rongxin Jiang
Yufeng Wang
Yaowu Chen
Jing Zhang
Tianming Liu

Funding

Assessing Large-scale Connectivities in Prenatal Cocaine Exposure Affected BrainsR01DA033393 · NIDA · UNIVERSITY OF GEORGIA · PI HU, XIAOPING P, LIU, TIANMING · 2012 to 2016
$1.6M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
NIA NIH HHS R01 AG-042599NIDA NIH HHS R01DA-033393
6 · The paper itself

Abstract

Modeling abnormal temporal dynamics of functional interactions in psychiatric disorders has been of great interest in the neuroimaging field, and thus a variety of methods have been proposed so far. However, the temporal dynamics and disease-related abnormalities of functional interactions within specific data-driven discovered subnetworks have been rarely explored yet. In this work, we propose a novel computational framework composed of an effective Bayesian connectivity change point model for modeling functional brain interactions and their dynamics simultaneously and an effective variant of nonnegative matrix factorization for assessing the functional interaction abnormalities within subnetworks. This framework has been applied on the resting state fmagnetic resonance imaging (fMRI) datasets of 23 children with attention-deficit/hyperactivity disorder (ADHD) and 45 normal control (NC) children, and has revealed two atomic functional interaction patterns (AFIPs) discovered for ADHD and another two AFIPs derived for NC. Together, these four AFIPs could be grouped into two pairs, one common pair representing the common AFIPs in ADHD and NC, and the other abnormal pair representing the abnormal AFIPs in ADHD. Interestingly, by comparing the abnormal AFIP pair, two data-driven abnormal functional subnetworks are derived. Strikingly, by evaluating the approximation based on the four AFIPs, all of the ADHD children were successfully differentiated from NCs without any false positive.

Indexed as

Brain MappingNonlinear DynamicsAttention Deficit Disorder with HyperactivityBayes TheoremBrainComputer SimulationFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleOxygenOxygenADHDbrain networksfunctional interactionnonnegative matrix factorizationtemporal dynamics

Identifiers

PMID24861961
PMCPMC6869011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.