Evidence map›Paper›PMID 24861157›Full record

ArticleNeurogastroenterology and motility2014

Esophageal distension during bolus transport: can it be detected by intraluminal impedance recordings?

J H Kim, R K Mittal, N Patel, M Ledgerwood, V Bhargava

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurogastroenterology and motility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Loop analysis of the anal sphincter complex in fecal incontinent patients using functional luminal imaging probe.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

J H KimDepartment of Medicine, Division of Gastroenterology, San Diego VA Health Care System & University of California, San Diego, CA, USA; Departments of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
R K Mittal
N Patel
M Ledgerwood
V Bhargava
UC San Diego Health System · USUniversity of California San Diego · US

Funding

Genesis of Esophageal Pain: Longitudinal Muscle Spasm and Wall IschemiaR01DK060733 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI MITTAL, RAVINDER K. · 2002 to 2016
$3.9M
Novel Electrical Impedance Methodology to Understand Functional DysphagiaR01DK109376 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MITTAL, RAVINDER K. · 2016 to 2020
$2.5M
NIDDK NIH HHS DK060733NIDDK NIH HHS R01 DK060733NIDDK NIH HHS R01 DK109376
6 · The paper itself

Abstract

backgroundEsophageal multiple intraluminal impedance (MII) measurement has been used to detect gastro-esophageal reflux and bolus transport. It is not clear if MII can detect changes in luminal cross sectional area (CSA) during bolus transport. Intraluminal ultrasound (US) images, MII, and high resolution manometry (HRM) were recorded simultaneously to determine temporal relationship between CSA and impedance during esophageal bolus transport and to define the relationship between peak distension and nadir impedance.

methodsStudies were conducted in five healthy subjects. MII, HRM, and US images were recorded 6 cm above LES. Esophageal distensions were studied during swallows and injections of 0.5 N saline bolus into the esophagus. KEY

resultsTemporal change in esophageal CSA correlates with changes in impedance (r-value: mean ± SD = -0.80 ± 0.08, range: -0.94 to -0.66). Drop in impedance during distension occurs as a two-step process; initial large drop associated with onset of CSA increase, followed by a small drop during which majority of the CSA increase occurs. Peak CSA and nadir impedance occur within 1 s of each other. Increase in swallow and injection volumes increased the CSA, had no effect on large drop but increased the small drop amplitude. We observed a significant correlation between peak CSA and nadir impedance (r = -0.90, p < 0.001) and a better correlation between peak CSA and inverse impedance (r = 0.94, p < 0.001). CONCLUSIONS & INFERENCES: Further studies are needed to confirm that intraluminal impedance recordings may be used to measure luminal CSA during esophageal bolus transport.

Indexed as

Electric ImpedanceAdultDeglutitionEsophagusFemaleHumansMalePeristalsisesophageal cross-sectional areaesophageal distensionesophageal peristalsismultiple intra luminal esophageal impedance

Identifiers

PMID24861157
PMCPMC4107335
OpenAlexW2120971989

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.