Evidence map›Paper›PMID 24860704›Full record

ArticlePeerJ2014

Characterisation of the horse transcriptome from immunologically active tissues.

Joanna Moreton, Sunir Malla, A Aziz Aboobaker, Rachael E Tarlinton, Richard D Emes

Abstract read
In one paragraph

Article in PeerJ, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. In search of epigenetic hallmarks of different tissues: an integrative omics study of horse liver, lung, and heart.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Genetic Susceptibility to Rhodococcus equi.Journal of veterinary internal medicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna MoretonAdvanced Data Analysis Centre, University of Nottingham, Sutton Bonington Campus , Loughborough , Leicestershire , UK ; Deep Seq, School of Life Sciences, University of Nottingham, Medical School, Queen's Medical Centre , Nottingham , UK ; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus , Loughborough , Leicestershire , UK.
Sunir MallaDeep Seq, School of Life Sciences, University of Nottingham, Medical School, Queen's Medical Centre , Nottingham , UK.
A Aziz AboobakerDepartment of Zoology, University of Oxford , Oxford , UK.
Rachael E TarlintonSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus , Loughborough , Leicestershire , UK.
Richard D EmesAdvanced Data Analysis Centre, University of Nottingham, Sutton Bonington Campus , Loughborough , Leicestershire , UK ; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus , Loughborough , Leicestershire , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system of the horse has not been well studied, despite the fact that the horse displays several features such as sensitivity to bacterial lipopolysaccharide that make them in many ways a more suitable model of some human disorders than the current rodent models. The difficulty of working with large animal models has however limited characterisation of gene expression in the horse immune system with current annotations for the equine genome restricted to predictions from other mammals and the few described horse proteins. This paper outlines sequencing of 184 million transcriptome short reads from immunologically active tissues of three horses including the genome reference "Twilight". In a comparison with the Ensembl horse genome annotation, we found 8,763 potentially novel isoforms.

Indexed as

Equus caballusRNA-SeqTranscriptome assembly

Identifiers

PMID24860704
PMCPMC4017814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.