Evidence map›Paper›PMID 24860598›Full record

ReviewFrontiers in genetics2014

Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells.

Dunja Lukovic, Victoria Moreno-Manzano, Martin Klabusay, Miodrag Stojkovic, Shomi S Bhattacharya, Slaven Erceg

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells.The Yale journal of biology and medicine · 2016
    Review
  7. 7SK small nuclear RNA inhibits cancer cell proliferation through apoptosis induction.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dunja LukovicRetina Group, Cell therapy and Regenerative Medicine, Centro Andaluz de Biología Molecular y Medicina Regenerativa Sevilla, Spain.
Victoria Moreno-ManzanoNeuronal and Tissue Regeneration Lab, Centro de Investigación Príncipe Felipe Valencia, Spain.
Martin KlabusayIntegrated Center of Cellular Therapy and Regenerative Medicine - International Clinical Research Center, St. Anne's University Hospital Brno Brno, Czech Republic.
Miodrag StojkovicSpebo Medical Leskovac, Serbia ; Human Genetics Department, Faculty of Medical Sciences, University of Kragujevac Kragujevac, Serbia.
Shomi S BhattacharyaRetina Group, Cell therapy and Regenerative Medicine, Centro Andaluz de Biología Molecular y Medicina Regenerativa Sevilla, Spain.
Slaven ErcegRetina Group, Cell therapy and Regenerative Medicine, Centro Andaluz de Biología Molecular y Medicina Regenerativa Sevilla, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have demonstrated the important role of non-coding RNAs as regulators of posttranscriptional processes, including stem cells self-renewal and neural differentiation. Human embryonic stem cells (hESCs) and induced pluripotent stem cells (ihPSCs) show enormous potential in regenerative medicine due to their capacity to differentiate to virtually any type of cells of human body. Deciphering the role of non-coding RNAs in pluripotency, self-renewal and neural differentiation will reveal new molecular mechanisms involved in induction and maintenances of pluripotent state as well as triggering these cells toward clinically relevant cells for transplantation. In this brief review we will summarize recently published studies which reveal the role of non-coding RNAs in pluripotency and neural differentiation of hESCs and ihPSC.

Indexed as

differentiationhuman embryonic stem cellsnon-coding RNApluripotencypluripotent stem cells

Identifiers

PMID24860598
PMCPMC4030195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.