Evidence map›Paper›PMID 24860494›Full record

ArticleFrontiers in aging neuroscience2014

Tai Chi Chuan optimizes the functional organization of the intrinsic human brain architecture in older adults.

Gao-Xia Wei, Hao-Ming Dong, Zhi Yang, Jing Luo, Xi-Nian Zuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 7 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 7 syntheses or guidelines pooled it, 108 citations in OpenAlex.

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  15. The Science of Tai Chi andJournal of integrative and complementary medicine · 2025
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gao-Xia WeiKey Laboratory of Behavioral Science, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Key Laboratory of Mental Health, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Laboratory for Functional Connectome and Development, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Magnetic Resonance Imaging Research Center, Institute of Psychology - Chinese Academy of Sciences Beijing, China.
Hao-Ming DongKey Laboratory of Behavioral Science, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Laboratory for Functional Connectome and Development, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; University of Chinese Academy of Sciences Beijing, China.
Zhi YangKey Laboratory of Behavioral Science, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Laboratory for Functional Connectome and Development, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Magnetic Resonance Imaging Research Center, Institute of Psychology - Chinese Academy of Sciences Beijing, China.
Jing LuoKey Laboratory of Mental Health, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Beijing Key Laboratory of Learning and Cognition, Department of Psychology, Capital Normal University Beijing, China.
Xi-Nian ZuoKey Laboratory of Behavioral Science, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Laboratory for Functional Connectome and Development, Institute of Psychology - Chinese Academy of Sciences Beijing, China ; Magnetic Resonance Imaging Research Center, Institute of Psychology - Chinese Academy of Sciences Beijing, China.
Institute of Psychology, Chinese Academy of Sciences · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether Tai Chi Chuan (TCC) can influence the intrinsic functional architecture of the human brain remains unclear. To examine TCC-associated changes in functional connectomes, resting-state functional magnetic resonance images were acquired from 40 older individuals including 22 experienced TCC practitioners (experts) and 18 demographically matched TCC-naïve healthy controls, and their local functional homogeneities across the cortical mantle were compared. Compared to the controls, the TCC experts had significantly greater and more experience-dependent functional homogeneity in the right post-central gyrus (PosCG) and less functional homogeneity in the left anterior cingulate cortex (ACC) and the right dorsal lateral prefrontal cortex. Increased functional homogeneity in the PosCG was correlated with TCC experience. Intriguingly, decreases in functional homogeneity (improved functional specialization) in the left ACC and increases in functional homogeneity (improved functional integration) in the right PosCG both predicted performance gains on attention network behavior tests. These findings provide evidence for the functional plasticity of the brain's intrinsic architecture toward optimizing locally functional organization, with great implications for understanding the effects of TCC on cognition, behavior and health in aging population.

Indexed as

aerobic exerciseexecutive functionfunctional homogeneitymeditationTai Chi Chuan

Identifiers

PMID24860494
PMCPMC4029006
OpenAlexW2141729898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.