Evidence map›Paper›PMID 24860459›Full record

ArticleFrontiers in human neuroscience2014

Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report.

Patrizio Sale, Fabrizio Stocchi, Daniele Galafate, Maria Francesca De Pandis, Domenica Le Pera, Ivan Sova, Manuela Galli, Calogero Foti, Marco Franceschini

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01668407 (Use of a Robot for the Rehabilitation of Walking in Patients With Parkinson's Disease.), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01668407 nacompletednot on this map

Use of a Robot for the Rehabilitation of Walking in Patients With Parkinson's Disease.

TypeinterventionalSponsorIRCCS San Raffaele RomaRan2012 to 2016Enrolled80ConditionsIdiopathic Parkinson's Disease, Progressive Supranuclear PalsyArmsRobot-Assisted Gait Training (RAGT), Treadmill Gait Training (TT)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Patrizio SaleDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Fabrizio StocchiDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Daniele GalafateDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Maria Francesca De PandisSan Raffaele Cassino Cassino, Italy.
Domenica Le PeraDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Ivan SovaDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Manuela GalliDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy ; Dipartimento di Elettronica, Informazione e Bioingegneria-Politecnico di Milano Milano, Italy.
Calogero FotiPhysical Rehabilitation Medicine Chair, Clinical Sciences and Translational Medicine DPT, Tor Vergata University Roma, Italy.
Marco FranceschiniDepartment of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
Istituto di Ricovero e Cura a Carattere Scientifico San RaffaeleIRCCS Ospedale San Raffaele · ITUniversità degli studi di Cassino e del Lazio Meridionale · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeProgressive supranuclear palsy (PSP) is a rare neurodegenerative disease clinically characterized by prominent axial extrapyramidal motor symptoms with frequent falls. Over the last years the introduction of robotic technologies to recover lower limb function has been greatly employed in the rehabilitative practice. This observational trial is aimed at investigating the changes in the main spatiotemporal following end-effector robot training in people with PSP.

methodPilot observational trial.

participantsFive cognitively intact participants with PSP and gait disorders.

interventionsPatients were submitted to a rehabilitative program of robot-assisted walking sessions for 45 min, 5 times a week for 4 weeks.

main outcome measuresThe spatiotemporal parameters at the beginning (T0) and at the end of treatment (T1) were recorded by a gait analysis laboratory.

resultsRobot training was feasible, acceptable and safe and all participants completed the prescribed training sessions. All patients showed an improvement in the gait spatiotemporal index (Mean velocity, Cadence, Step length, and Step width) (T0 vs. T1).

conclusionsRobot training is a feasible and safe form of rehabilitation for cognitively intact people with PSP. The lack of side effects and the positive results in the gait parameter index in all patients support the recommendation to extend the trials of this treatment. Further investigation regarding the effectiveness of robot training in time is necessary.

trial registrationClinicalTrials.gov NCT01668407.

Indexed as

gait analysislower limbprogressive supranuclear palsyPSProbot

Identifiers

PMID24860459
PMCPMC4029018
OpenAlexW2000047714

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.