Evidence map›Paper›PMID 24859540›Full record

ArticleBMJ case reports2014

Autoimmune pulmonary proteinosis in a Chilean teenager, a rare aetiology of interstitial lung disease.

Alexis Strickler, Maria Lina Boza, Andres Koppmann, Sergio Gonzalez

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexis StricklerDepartment of Service of Paediatrics, Puerto Montt Hospital Chile, Puerto Montt, Chile.
Maria Lina BozaDepartment of Paediatric Neumology, San Borja Arriarán Hospital, University of Chile, Santiago, Chile.
Andres KoppmannDepartment of Paediatric Neumology, San Borja Arriarán Hospital, University of Chile, Santiago, Chile.
Sergio GonzalezDepartment of Pathology, Pontifical Catholic University of Chile, Santiago, Chile.
University of Chile · CLPontificia Universidad Católica de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial lung disease (ILD) is rare and encompasses a heterogeneous group of diseases, and is even rarer in children than in adults. ILDs compromise more than 100 different entities, including pulmonary alveolar proteinosis (PAP). There are many causes of PAP in children, including surfactant protein gene mutations (SFTPB, SFTPC, ABCA3, TTF-1), GMCSF receptor mutations and antigranulocyte-macrophage colony-stimulating factor autoantibodies. We report a case of a 13-year-old Chilean girl who presented with an 8-month history of progressive exercise intolerance, fatigability and diminished school performance. Physical examination revealed resting tachypnoea, a few basal bilateral inspiratory crackles, and hypoxaemia on minimal exertion. Clinical suspicion and evaluation, including international collaboration, led to the diagnosis of autoimmune PAP and specific therapy for the condition.

Indexed as

AdolescentAutoimmune DiseasesBronchoalveolar LavageChileFemaleHumansLungPulmonary Alveolar ProteinosisTomography, X-Ray Computed

Identifiers

PMID24859540
PMCPMC4039768
OpenAlexW2324756969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.