Evidence map›Paper›PMID 24859323›Full record

ArticleJournal of tropical pediatrics2014

Predominance of rotavirus G1[P8] genotype among under-five children with gastroenteritis in Mwanza, Tanzania.

Adolfine Hokororo, Benson R Kidenya, Jeremiah Seni, Seheri Mapaseka, Jeffrey Mphahlele, Stephen E Mshana

Open access · bronzeAbstract read
In one paragraph

Article in Journal of tropical pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Whole genome detection of rotavirus mixed infections in human, porcine and bovine samples co-infected with various rotavirus strains collected from sub-Saharan Africa.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015
    Article
  6. Review of global rotavirus strain prevalence data from six years post vaccine licensure surveillance: is there evidence of strain selection from vaccine pressure?Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Adolfine HokororoDepartment of Pediatrics and Child Health Bugando Medical Centre, P.O.Box 1370, Mwanza, Tanzania.
Benson R KidenyaDepartment of Biochemistry and Molecular Biology Catholic University of Health and Allied Sciences, P.O.Box 1464, Mwanza, Tanzania.
Jeremiah SeniDepartment of Microbiology and Immunology Catholic University of Health and Allied Sciences, P.O.Box 1464, Mwanza, Tanzania.
Seheri MapasekaDepartment of Virology, University of Limpopo, College of Health and Allied Sciences, P.O.Box 173, Limpopo, South Africa.
Jeffrey MphahleleDepartment of Virology, University of Limpopo, College of Health and Allied Sciences, P.O.Box 173, Limpopo, South Africa.
Stephen E MshanaDepartment of Microbiology and Immunology Catholic University of Health and Allied Sciences, P.O.Box 1464, Mwanza, Tanzania mshana72@yahoo.com.
Catholic University of Health and Allied Sciences · TZUniversity of Limpopo · ZABugando Medical Centre · TZ

Funding

Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
FIC NIH HHS R25 TW009337
6 · The paper itself

Abstract

We analyzed stool samples from underfives with gastroenteritis for rotavirus infection between January 2010 and June 2011. A total of 393 stool specimens were examined for rotavirus infection using enzyme-linked immunosorbent assay (ELISA). Hundred selected positive specimens were genotyped using multiplex polymerase chain reaction. Out of 393 underfives, 194 (49.4%) had rotavirus infection, with 96.9% of infected underfives being <2 years. Underfives infected with rotavirus had prolonged hospital stay than those without rotavirus infection (P = 0.0001). G1 was the most predominant G type (59%) followed by G8 (13%) while P[8] was the most predominant P type (25%). In single-type infection, common G-P combinations were G1P[8] (24%) and G1P[6] (17%). Common mixed infections were G1/G8 (16%) and P4/P8 (13%). G1 genotype is common among underfives with gastroenteritis in Mwanza. Diversity of genotypes causing gastroenteritis in Mwanza necessitates a continuous surveillance after the introduction of RotaRix® vaccine.

Indexed as

Child, PreschoolCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFecesFemaleGastroenteritisGenotypeHumansInfantMaleMultiplex Polymerase Chain ReactionProspective StudiesRNA, ViralRotavirusRotavirus InfectionsTanzaniaRNA, ViralgenotypesrotavirusTanzania

Identifiers

PMID24859323
PMCPMC4481713
OpenAlexW2323734872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.