ArticlePharmacoEconomics2014
The burden of disease in rheumatoid arthritis.
Article in PharmacoEconomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 6 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Real-World Evidence for Baricitinib in the Treatment of Rheumatoid Arthritis in Spain: A Systematic Literature Review.Advances in therapy · 2025Pooled it
- A Systematic Review of Job Loss Prevention Interventions for Persons with Inflammatory Arthritis.Journal of occupational rehabilitation · 2021Pooled it
- The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review.Rheumatology international · 2021Pooled it
- Patients with rheumatoid arthritis have an increased risk of incident chronic kidney disease: a systematic review and meta-analysis of cohort studies.International urology and nephrology · 2020Pooled it
- Meta-analysis of IL-17 inhibitors in two populations of rheumatoid arthritis patients: biologic-naïve or tumor necrosis factor inhibitor inadequate responders.Clinical rheumatology · 2019Pooled it
- Modeled Health Economic Impact of a Hypothetical Certolizumab Pegol Risk-Sharing Scheme for Patients with Moderate-to-Severe Rheumatoid Arthritis in Finland.Advances in therapy · 2017Pooled it
- Effectiveness and cost-effectiveness of a multimodal, physiotherapist-led, vocational intervention for people with rheumatoid arthritis or axial spondyloarthritis and a reduced work ability: a randomized, controlled trial.Rheumatology international · 2025Trial
- The association of fatigue, pain, depression and anxiety with work and activity impairment in immune mediated inflammatory diseases.PloS one · 2018Trial
- Trial
- Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity.BMC musculoskeletal disorders · 2017Trial
- One Year Effects of a Workplace Integrated Care Intervention for Workers with Rheumatoid Arthritis: Results of a Randomized Controlled Trial.Journal of occupational rehabilitation · 2017Trial
- AI-Derived Carpal Compactness Metrics as Quantitative Imaging Measures of Global Carpal Architecture in Early Rheumatoid Arthritis.Journal of imaging · 2026Article
- Healthcare Professionals' Experiences with Vocational Rehabilitation for People with Inflammatory Arthritis.Journal of occupational rehabilitation · 2026Article
- Real-World Analysis of Initial Clinical Response and Future Outcomes Among Patients with Rheumatoid Arthritis Initiating and Remaining on a First-Line Tumor Necrosis Factor Inhibitor in the United States.Rheumatology and therapy · 2026Article
- The Number of Pregnancies is Associated with an Increased Risk of Rheumatoid Arthritis: Evidence from NHANES 2015-2018.International journal of women's health · 2026Article
- Cross-cultural adaptation and psychometric testing of the Turkish Version of the Workplace Activity Limitations Scale (WALS) in people with inflammatory arthritis.Rheumatology advances in practice · 2026Article
- Preferences regarding technology to unobtrusively monitor symptoms in rheumatoid arthritis: a qualitative study using focus group discussions.Rheumatology international · 2025Article
- Cost-Effectiveness Analysis of Recombinant Tumor Necrosis Factor Receptor: Fc Fusion Protein as First-Line Treatment for Active Rheumatoid Arthritis in China.Healthcare (Basel, Switzerland) · 2025Article
- Economic Burden of Rheumatoid Arthritis in Iran: A Societal Perspective.Public health challenges · 2025Article
- Depression, Anxiety, and Health-Related Quality of Life in Adults with Rheumatoid Arthritis: Findings from a National Survey.Journal of clinical medicine · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory disease which, if left untreated, leads to functional disability, pain, reduced health-related quality of life and premature mortality. Between 0.5% and 1% of the population are affected worldwide, and between 25 and 50 new cases evolve in a population of 100,000. Practically all patients with RA require initiation with disease-modifying antirheumatic treatment to retard or stop progression, control disease manifestations and reduce the disease burden. If disease course is monitored with adjustment of medication, lifestyle factors, and exercise, as well as physical activity levels, co-morbidities may be prevented in the course of RA. During the last decade, major progress has been made in treating RA through early identification and treatment of the disease. Many patients still experience premature work disability and co-morbidities. For societies, the economic burden of RA is high in terms of direct and indirect costs, including modern drug treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.