Evidence map›Paper›PMID 24858531›Full record

ArticleEye (London, England)2014

Glaucoma prescribing trends in England 2000 to 2012.

A J Connor, S G Fraser

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. The Use of Generic Medications for Glaucoma.Journal of ophthalmology · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. [Possibilities and limitations of eye drops for glaucoma therapy].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2016
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

A J ConnorDepartment of Ophthalmology, Royal Victoria Infirmary, Newcastle Upon Tyne, Tyne and Wear, UK.
S G FraserSunderland Eye Infirmary, Sunderland, Tyne and Wear, UK.
Royal Victoria Infirmary · GBSunderland Eye Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn 2009, the National Institute for Clinical Excellence (NICE) published guidance on the treatment of ocular hypertension and glaucoma. The aim of the present study was to describe the impact this guidance had on glaucoma prescribing and to describe recent prescribing trends in England.

methodPrescribing cost analysis data held by NHS Business Authority for the years 2000-2012 was analysed.

resultsThe number of prescriptions dispensed increased by 67% from 4.76 million in 2000 to 7.96 million in 2012. Over the same time period, drug costs increased by 88% from £55.2 million to £103.7 million. Prescriptions for prostaglandin analogues increased fourfold, while there was a threefold decrease in the use of beta-blockers. The most commonly prescribed glaucoma medication was latanoprost. The introduction of generic latanoprost in 2012 more than halved the cost associated with this medication. NICE guidance appeared to have had no effect on the total number of prescriptions or the classes of medications prescribed.

conclusionThe introduction of the NICE guidelines did not change glaucoma prescribing practice, although it is not clear whether this represents non-adherence to the guidelines or whether the guidelines embodied pre-existing practice.

Indexed as

Administration, TopicalAntihypertensive AgentsDrug CostsDrug PrescriptionsEnglandGlaucomaGuideline AdherenceHumansIntraocular PressureOcular HypertensionOphthalmic SolutionsPractice Guidelines as TopicPractice Patterns, Physicians'Antihypertensive AgentsOphthalmic Solutions

Identifiers

PMID24858531
PMCPMC4094806
OpenAlexW2032524220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.