ReviewNeurobiology of learning and memory2015
From ventral-medial to dorsal-lateral striatum: neural correlates of reward-guided decision-making.
Review in Neurobiology of learning and memory, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
123 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Neurofunctional representations of instrumental learning in psychosis: a meta-analysis of neuroimaging studies.Psychological medicine · 2025Pooled it
- Altered value-based decision-making in anorexia nervosa: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- Shared and distinct neural activity during anticipation and outcome of win and loss: A meta-analysis of the monetary incentive delay task.NeuroImage · 2022Pooled it
- Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies.Addiction biology · 2022Pooled it
- Altered brain activation during reward anticipation in bipolar disorder.Translational psychiatry · 2022Pooled it
- Frontostriatal circuitry as a target for fMRI-based neurofeedback interventions: A systematic review.Frontiers in human neuroscience · 2022Pooled it
- Pain Catastrophizing Is Associated With Increased Alcohol Cue-Elicited Neural Activity Among Individuals With Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Trial
- Histone deacetylase inhibitor sodium butyrate increases risk-taking during acquisition of the rat gambling task.Psychopharmacology · 2026Article
- Brain-Inspired Multi-Pathway Motion Decision-Making for Obstacle Avoidance of Humanoid Arms.Biomimetics (Basel, Switzerland) · 2026Article
- Intermittency and Predictability of a Cafeteria Diet Shape Food Intake, Adiposity, and Neurobehavioral Outcomes in Rats.Nutrients · 2026Article
- The neuroanatomy and connectivity of the ventral striatum and ventral capsule area in the Göttingen minipig.Brain structure & function · 2026Article
- Prefrontal modulation of striatal engagement: a hierarchical framework for goal-directed behavior.Communications biology · 2026Review
- Reward circuit function and treatment outcome following vALIC deep brain stimulation in treatment-resistant depression.Molecular psychiatry · 2026Article
- Striatal Nitric Oxide Activity Better Predicts Motor Disability Than Proto-Oncogenes.The European journal of neuroscience · 2026Article
- Nanoscale synaptic remodeling at corticostriatal circuits predicts flexible action control.bioRxiv : the preprint server for biology · 2025Article
- Ventral striatal astrocytes contribute to reinforcement learning.bioRxiv : the preprint server for biology · 2025Article
- Reward-reset interval timing drives patch foraging decisions through neural state transitions in dorsomedial striatum.bioRxiv : the preprint server for biology · 2025Article
- Theory-based strategies to enhance interventions for smoking: Relevance to a digital intervention.Behaviour research and therapy · 2025Review
- Behavioral inflexibility through overtraining is mediated by reduced mGluR1/5 signaling capacity in the dorsolateral striatum.PLoS biology · 2025Article
- Anterior Cingulate Cortex Contributes to the Hyperlocomotion under Nitrogen Narcosis.Neuroscience bulletin · 2025Article
63 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The striatum is critical for reward-guided and habitual behavior. Anatomical and interference studies suggest a functional heterogeneity within striatum. Medial regions, such as nucleus accumbens core and dorsal medial striatum play roles in goal-directed behavior, while dorsal lateral striatum is critical for control of habitual action. Subdivisions of striatum are topographically connected with different cortical and subcortical structures forming channels that carry information related to limbic, associative, and sensorimotor functions. Here, we describe data showing that as one progresses from ventral-medial to dorsal-lateral striatum, there is a shift from more prominent value encoding to activity more closely related to associative and motor aspects of decision-making. In addition, we will describe data suggesting that striatal circuits work in parallel to control behavior and that regions within striatum can compensate for each other when functions are disrupted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.