ArticleMaterials science & engineering. C, Materials for biological applications2014
Creep of trabecular bone from the human proximal tibia.
Article in Materials science & engineering. C, Materials for biological applications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Medial Malleolar Fracture Fixation with Stainless Steel, Titanium, Magnesium, and PLGA Screws: A Finite Element Analysis.Journal of functional biomaterials · 2026Article
- Trabecular Architecture of the Proximal Tibia in Extant Hominids.American journal of biological anthropology · 2025Article
- Trabecular architecture of the distal femur in extant hominids.Journal of anatomy · 2024Article
- Biomechanics of the Human Osteochondral Unit: A Systematic Review.Materials (Basel, Switzerland) · 2024Review
- Usefulness of non-slip element percutaneous transluminal angioplasty scoring balloons in treating severe calcified lesions of the carotid artery for carotid artery stenting: A case report.Surgical neurology international · 2024Article
- Comparison of four different screw configurations for the fixation of Fulkerson osteotomy: a finite element analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Article
- Characterization of Ultralow Density Cellular Solids: Lessons from 30 years of Bone Biomechanics Research.Advanced engineering materials · 2021Article
- Effect of cartilage thickness mismatch in osteochondral grafting from knee to talus on articular contact pressures: A finite element analysis.Joint diseases and related surgery · 2021Article
- Loading capacity of dynamic knee spacers: a comparison between hand-moulded and COPAL spacers.BMC musculoskeletal disorders · 2019Article
- Article
- The relationship of whole human vertebral body creep to geometric, microstructural, and material properties.Journal of biomechanics · 2018Article
- Time Dependent Behaviour of Trabecular Bone at Multiple Load Levels.Annals of biomedical engineering · 2017Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Creep is the deformation that occurs under a prolonged, sustained load and can lead to permanent damage in bone. Creep in bone is a complex phenomenon and varies with type of loading and local mechanical properties. Human trabecular bone samples from proximal tibia were harvested from a 71-year old female cadaver with osteoporosis. The samples were initially subjected to one cycle load up to 1% strain to determine the creep load. Samples were then loaded in compression under a constant stress for 2h and immediately unloaded. All tests were conducted with the specimens soaked in phosphate buffered saline with proteinase inhibitors at 37 °C. Steady state creep rate and final creep strain were estimated from mechanical testing and compared with published data. The steady state creep rate correlated well with values obtained from bovine tibial and human vertebral trabecular bone, and was higher for lower density samples. Tissue architecture was analyzed by micro-computed tomography (μCT) both before and after creep testing to assess creep deformation and damage accumulated. Quantitative morphometric analysis indicated that creep induced changes in trabecular separation and the structural model index. A main mode of deformation was bending of trabeculae.
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Registered trials
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