ArticleJournal of biomechanics2014
Subject-specific planning of femoroplasty: a combined evolutionary optimization and particle diffusion model approach.
Article in Journal of biomechanics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- A Surgical Robotic System for Osteoporotic Hip Augmentation: System Development and Experimental Evaluation.IEEE transactions on medical robotics and bionics · 2023Article
- A biomechanically-guided planning and execution paradigm for osteoporotic hip augmentation: Experimental evaluation of the biomechanics and temperature-rise.Clinical biomechanics (Bristol, Avon) · 2021Article
- Fiducial-Free 2D/3D Registration for Robot-Assisted Femoroplasty.IEEE transactions on medical robotics and bionics · 2020Article
- Finite element models for fracture prevention in patients with metastatic bone disease. A literature review.Bone reports · 2020Review
- Significance of preoperative planning for prophylactic augmentation of osteoporotic hip: A computational modeling study.Journal of biomechanics · 2019Article
- In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium-based implant confers immediate biomechanical integrity.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- PRELIMINARY MECHANICAL TEST OF PROXIMAL FEMUR REINFORCEMENT WITH CEMENTED X-SHAPED PMMA.Acta ortopedica brasileira · 2018Article
- Discrete particle model for cement infiltration within open-cell structures: Prevention of osteoporotic fracture.PloS one · 2018Article
- Prophylactic augmentation of the osteoporotic proximal femur-mission impossible?BoneKEy reports · 2016Review
- Subject-specific planning of femoroplasty: an experimental verification study.Journal of biomechanics · 2015Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A potential effective treatment for prevention of osteoporotic hip fractures is augmentation of the mechanical properties of the femur by injecting it with agents such as (PMMA) bone cement - femoroplasty. The operation, however, is only in research stage and can benefit substantially from computer planning and optimization. We report the results of computational planning and optimization of the procedure for biomechanical evaluation. An evolutionary optimization method was used to optimally place the cement in finite element (FE) models of seven osteoporotic bone specimens. The optimization, with some inter-specimen variations, suggested that areas close to the cortex in the superior and inferior of the neck and supero-lateral aspect of the greater trochanter will benefit from augmentation. We then used a particle-based model for bone cement diffusion simulation to match the optimized pattern, taking into account the limitations of the actual surgery, including limited volume of injection to prevent thermal necrosis. Simulations showed that the yield load can be significantly increased by more than 30%, using only 9 ml of bone cement. This increase is comparable to previous literature reports where gross filling of the bone was employed instead, using more than 40 ml of cement. These findings, along with the differences in the optimized plans between specimens, emphasize the need for subject-specific models for effective planning of femoral augmentation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.