ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2014
Late-life depression and cardiovascular disease burden: examination of reciprocal relationship.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Longitudinal association between cardiovascular risk factors and depression in young people: a systematic review and meta-analysis of cohort studies.Psychological medicine · 2023Pooled it
- Associations of transitions in frailty and depressive symptoms with the risk of cardiovascular disease in adults with hypertension: findings from three aging cohorts.The journal of nutrition, health & aging · 2026Article
- Mental Health Service use and Expenditures among Medicare Beneficiaries with Depression, Diabetes and Heart Disease after Cost-sharing Parity.Journal of general internal medicine · 2026Article
- Associations of Midlife Vascular Risk Factors With Late-Life Depressive Symptoms: Findings From the ARIC Study.Journal of the American Heart Association · 2026Article
- The effect of psychotherapy on the multivariate association between insomnia and depressive symptoms in late-life depression.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Association of Depression Dimensions With Cognitive Functioning in Community-Dwelling Oldest-Old Adults: The LifeAfter90 Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Comparing the Association Between Depressive Symptoms and Cardiovascular Disease Among the Middle-Aged and Elderly Population: A National Survey of 9,049 Subjects Based on the Indonesian Family Life Survey-5.Vascular health and risk management · 2025Article
- Cardiovascular Disease, Depressive Symptoms, and Heart Failure in Mexican American Aged 75 Years and Older During 12 Years of Follow Up.Journal of affective disorders reports · 2024Article
- Research status and global trends of late-life depression from 2004 to 2023: bibliometric analysis.Frontiers in aging neuroscience · 2024Article
- Gender differences in the association between cardiovascular diseases and major depressive disorder among older adults in India.Dialogues in health · 2023Article
- The Prevalence of Depression and Anxiety in Heart Failure Patients in Saudi Arabia: An Original Study.Cureus · 2023Article
- Spotlight on the Challenges of Depression following Retirement and Opportunities for Interventions.Clinical interventions in aging · 2022Review
- Association between depressive symptoms and pulse wave velocity is mediated by increased adiposity in older adults with type 2 diabetes.Journal of psychiatry & neuroscience : JPN · 2021Article
- Untreated depressive symptoms significantly worsen quality of life in old age and may lead to the misdiagnosis of dementia: a cross-sectional study.Annals of general psychiatry · 2020Article
- Higher dietary inflammation is associated with increased odds of depression independent of Framingham Risk Score in the National Health and Nutrition Examination Survey.Nutrition research (New York, N.Y.) · 2018Article
- Impact of Anxiety and Depression on Physical Health Condition and Disability in an Elderly Korean Population.Psychiatry investigation · 2017Article
- Vascular depression consensus report - a critical update.BMC medicine · 2016Article
- The prevalence of risk factors for cardiovascular diseases among Polish surgical patients over 65 years.Clinical interventions in aging · 2016Article
- Using Administrative Data to Examine Health Disparities and Outcomes in Neurological Diseases of the Elderly.Current neurology and neuroscience reports · 2015Review
- Prevalence and Predictors of Depression in Korean American Elderly: Findings from the Memory and Aging Study of Koreans (MASK).The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectivesEmpirical studies of the relationship between depression and cardiovascular disease (CVD) tend to be limited to examination of one-way relationships. This study assessed both cross-sectional association and longitudinal reciprocal relationships between late-life depressive symptoms and CVD.
methodsThe National Health and Aging Trends Study waves 1 (T1) and 2 (T2, one year later) provided the data. The study sample (N = 5,414) represented Medicare beneficiaries aged 65 years or older. We fit structural equation models to examine: 1) cross-sectional association between depression and CVD at each wave; and 2) longitudinal reciprocal relationship between T1 depression and T2 CVD and between T1 CVD and T2 depression.
resultsAt T1, 28.6% reported a CVD diagnosis, and at T2, 4.9% reported having had a new diagnosis or new episode of heart attack or heart disease and 2.2% reported having had a stroke since T1. In addition to significant cross-sectional relationships between depression and CVD, T1 CVD had significant impact on T2 depressive symptoms, and T1 depressive symptoms had significant impact on T2 CVD, with a 1-point increase in depressive symptom score increasing the odds of having a new CVD diagnosis or episode by 21%.
conclusionsThe care of older adults with CVD and/or depression needs to include interventions focusing on lifestyle and psychological factors that can reduce risks for both CVD and depression. Depression prevention and treatment also needs to be an integral part of CVD prevention and management.
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