Trial reportClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2015
Lateralization and localization of epilepsy related hemodynamic foci using presurgical fMRI.
Trial report in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Spatio-temporal independent component classification for localization of seizure onset zone.Frontiers in neurology · 2025Article
- Disentanglement of Resting State Brain Networks for Localizing Epileptogenic Zone in Focal Epilepsy.Brain topography · 2024Article
- A DEEP LEARNING FRAMEWORK TO LOCALIZE THE EPILEPTOGENIC ZONE FROM DYNAMIC FUNCTIONAL CONNECTIVITY USING A COMBINED GRAPH CONVOLUTIONAL AND TRANSFORMER NETWORK.Proceedings. IEEE International Symposium on Biomedical Imaging · 2023Article
- DeepEZ: A Graph Convolutional Network for Automated Epileptogenic Zone Localization From Resting-State fMRI Connectivity.IEEE transactions on bio-medical engineering · 2023Article
- The expert's knowledge combined with AI outperforms AI alone in seizure onset zone localization using resting state fMRI.Frontiers in neurology · 2023Article
- Epileptic focus localization using transfer learning on multi-modal EEG.Frontiers in computational neuroscience · 2023Article
- Common functional connectivity alterations in focal epilepsies identified by machine learning.Epilepsia · 2022Article
- Automated seizure onset zone locator from resting-state functional MRI in drug-resistant epilepsy.Frontiers in neuroimaging · 2022Article
- Modulation of epileptic networks by transient interictal epileptic activity: A dynamic approach to simultaneous EEG-fMRI.NeuroImage. Clinical · 2020Article
- Article
- Characterization of functional brain activity and connectivity using EEG and fMRI in patients with sickle cell disease.NeuroImage. Clinical · 2017Article
- Delineating potential epileptogenic areas utilizing resting functional magnetic resonance imaging (fMRI) in epilepsy patients.Neurocase · 2016Article
- Genetic Programming and Frequent Itemset Mining to Identify Feature Selection Patterns of iEEG and fMRI Epilepsy Data.Engineering applications of artificial intelligence · 2015Article
- Thalamocortical relationship in epileptic patients with generalized spike and wave discharges--A multimodal neuroimaging study.NeuroImage. Clinical · 2015Article
- Network analysis of EEG related functional MRI changes due to medication withdrawal in focal epilepsy.NeuroImage. Clinical · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveThe aim was to develop a method for the purpose of localizing epilepsy related hemodynamic foci for patients suffering intractable focal epilepsy using task-free fMRI alone.
methodsWe studied three groups of subjects: patients with intractable focal epilepsy, healthy volunteers performing motor tasks, and healthy volunteers in resting state. We performed spatial independent component analysis (ICA) on the fMRI alone data and developed a set of IC selection criteria to identify epilepsy related ICs. The method was then tested in the two healthy groups.
resultsIn seven out of the nine surgery patients, identified ICs were concordant with surgical resection. Our results were also consistent with presurgical evaluation of the remaining one patient without surgery and may explain why she was not suitable for resection treatment. In the motor task study of ten healthy subjects, our method revealed components with concordant spatial and temporal features as expected from the unilateral motor tasks. In the resting state study of seven healthy subjects, the method successfully rejected all components in four out of seven subjects as non-epilepsy related components.
conclusionThese results suggest the lateralization and localization value of fMRI alone in presurgical evaluation for patients with intractable unilateral focal epilepsy. SIGNIFICANCE: The proposed method is noninvasive in nature and easy to implement. It has the potential to be incorporated in current presurgical workup for treating intractable focal epilepsy patients.
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