Evidence map›Paper›PMID 24856171›Full record

ReviewTherapeutic delivery2014

Mechanisms of microbubble-facilitated sonoporation for drug and gene delivery.

Zhenzhen Fan, Ronald E Kumon, Cheri X Deng

Registry-linked trialAbstract readReview
In one paragraph

Review in Therapeutic delivery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02233205 (Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Liver Metastases From Gastrointestinal Tumors and Pancreatic Carcinoma), which is not on this map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02233205 phase1 / phase2unknown statusnot on this map

Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Liver Metastases From Gastrointestinal Tumors and Pancreatic Carcinoma

TypeinterventionalSponsorPeking University Cancer Hospital & InstituteRan2014 to 2016Enrolled18ConditionsGastrointestinal NeoplasmsArmsultrasonic microbubbles, platinum and gemcitabine
3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Article
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  7. Review
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  17. Article
  18. Analyzing Gene Expression After Administration of Low-Intensity Therapeutic Ultrasound in Human Islet Cells.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2024
    Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhenzhen FanInstitute of Acoustics, Chinese Academy of Sciences, No. 21 Beisihuanxi Road, Beijing, 100190, China.
Ronald E Kumon
Cheri X Deng

Funding

Mechanisms of ultrasound mediated intracellular drug and gene deliveryR01CA116592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DENG, CHERI X · 2005 to 2009
$1.4M
NCI NIH HHS CA116592NCI NIH HHS R01 CA116592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Transfer TechniquesMicrobubblesUltrasonicsAnimalsBiological TransportCell Membrane PermeabilityDrug Delivery SystemsHumansPorosity

Identifiers

PMID24856171
PMCPMC4116608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.