Evidence map›Paper›PMID 24856136›Full record

ArticleChemistry & biology2014

Nitric oxide and histone acetylation-shaping craniofacial development.

Libera Berghella, Pier Lorenzo Puri

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. The role of gasotransmitters in neonatal physiology.Nitric oxide : biology and chemistry · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Libera BerghellaEpigenetics & Regenerative Medicine, IRCCS Fondazione Santa Lucia, 00142 Rome, Italy.
Pier Lorenzo PuriEpigenetics & Regenerative Medicine, IRCCS Fondazione Santa Lucia, 00142 Rome, Italy; Development, Aging and Regeneration (DAR) Program, Sanford-Burnham Medical Research Institute, Sanford Children's Health Research Center, La Jolla, CA 92037, USA. Electronic address: lpuri@sanfordburnham.org.
Fondazione Santa Lucia · ITSanford Burnham Prebys Medical Discovery Institute · US

Funding

Pathogenic Alterations of the 3D Epigenetic Landscape in Dystrophin-Deficient Skeletal Muscles and Reversal by Dystrophin Re-ExpressionR01AR056712 · NIAMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Pier Lorenzo Puri · 2009 to 2026
$7.3M
Signal-dependent switch of SWI/SNF by miRNAs & control of muscle stem cell fateR01AR052779 · NIAMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI PURI, PIER LORENZO · 2006 to 2015
$4.1M
NIAMS NIH HHS R01 AR052779NIAMS NIH HHS R01 AR056712
6 · The paper itself

Abstract

Previous work linked nitric oxide (NO) signaling to histone deacetelyases (HDACs) in the control of tissue homeostasis and suggested that deregulation of this signaling contributes to human diseases. In the previous issue of Chemistry & Biology, Kong and colleagues showed that coordinated NO signaling and histone acetylation are required for proper cranial neural crest development and craniofacial morphogenesis and suggested that alterations of NO/acetylation network can contribute to the pathogenesis of craniofacial malformations.

Indexed as

MorphogenesisAnimalsHistonesNeural CrestNitric OxideZebrafishHistonesNitric Oxide

Identifiers

PMID24856136
PMCPMC4114503
OpenAlexW2010162861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.