ArticleCell & developmental biology2014
Roles of Iroquois Transcription Factors in Kidney Development.
Article in Cell & developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions.Nature genetics · 2026Article
- Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancer.Clinical epigenetics · 2021Article
- Advances in understanding vertebrate nephrogenesis.Tissue barriers · 2020Article
- IRX3 and IRX5 collaborate during ovary development and follicle formation to establish responsive granulosa cells in the adult mouse†.Biology of reproduction · 2020Article
- Tfap2a is a novel gatekeeper of nephron differentiation during kidney development.Development (Cambridge, England) · 2019Article
- The Pronephros; a Fresh Perspective.Integrative and comparative biology · 2019Review
- Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development.Scientific reports · 2019Article
- The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis.The Journal of pathology · 2019Article
- Homeogene emx1 is required for nephron distal segment development in zebrafish.Scientific reports · 2018Article
- EF-hand domain containing 2 (Efhc2) is crucial for distal segmentation of pronephros in zebrafish.Cell & bioscience · 2018Article
- Scaling up to studyCancer cell & microenvironment · 2018Article
- ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development.Scientific reports · 2017Article
- Growing evidence suggests WT1 effects in the kidney development are modulated by Hsp70/NO interaction.Journal of nephrology · 2017Review
- The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish.Developmental biology · 2017Article
- Article
- Caudal migration and proliferation of renal progenitors regulates early nephron segment size in zebrafish.Scientific reports · 2016Article
- Antennas of organ morphogenesis: the roles of cilia in vertebrate kidney development.Genesis (New York, N.Y. : 2000) · 2016Review
- Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development.Developmental biology · 2016Article
- Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish.Developmental biology · 2015Article
- Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta.Developmental biology · 2014Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
Congenital anomalies of the kidney and urinary tract (CAKUT) affect 1/500 live births. CAKUT lead to end stage renal failure in children, and are associated with high morbidity rates. Understanding the mechanisms of kidney development, and that of other associated urogenital tissues, is crucial to the prevention and treatment of CAKUT. The kidney arises from self-renewing mesenchymal renal stem cells that produce nephrons, which are the principal functional units of the organ. To date, the genetic and cellular mechanisms that control nephrogenesis have remained poorly understood. In recent years, developmental studies using amphibians and zebrafish have revealed that their simple embryonic kidney, known as the pronephros, is a useful paradigm for comparative studies of nephron ontogeny. Here, we discuss the new found roles for
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.