ArticleMedical mycology case reports2014
Voriconazole associated torsades de pointes in two adult patients with haematological malignancies.
Article in Medical mycology case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization.Clinical pharmacology and therapeutics · 2017Trial
- Rare clinical presentation of invasive pulmonary aspergillosis in patient with early-stage lung cancer: a case report.Frontiers in medicine · 2026Article
- Recommendations on the use of azole antifungals in hematology-oncology patients.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023Review
- COVID-19 associated with pulmonary aspergillosis: A literature review.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2021Review
- Voriconazole-induced QT prolongation among hemato-oncologic patients: clinical characteristics and risk factors.European journal of clinical pharmacology · 2017Article
- [Ventricular tachyarrhythmia as a side effect of pharmacotherapy].Herzschrittmachertherapie & Elektrophysiologie · 2017Review
- New facets of antifungal therapy.Virulence · 2017Review
- Drug-induced proarrhythmia: risk factors and electrophysiological mechanisms.Nature reviews. Cardiology · 2016Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Voriconazole can prolong the QT interval contributing to life-threatening cardiac arrhythmia. Torsades de pointes is an uncommon but serious complication of voriconazole use which may be under-recognised. We present torsades de pointes in two patients with underlying haematological malignancy being treated for invasive fungal infection with voriconazole. Patients receiving voriconazole should be screened and monitored for evidence of QT prolongation, and if prolongation detected, consideration given to alternative treatments or more intensive cardiac monitoring.
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Registered trials
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