ArticleDermatology practical & conceptual2014
Papulonecrotic tuberculid-clinicopathologic and molecular features of 12 Indian patients.
Article in Dermatology practical & conceptual, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Cutaneous Tuberculosis in the Modern Era: A Case of Lupus Vulgaris with Surgical Management and a Review of Clinical Spectrum, Diagnostic Challenges, and Malignant Potential.Journal of clinical medicine · 2026Article
- A painful pustular eruption after initiation of rifampin, isoniazid, pyrazinamide and ethambutol therapy.JAAD case reports · 2025Article
- Papulonecrotic tuberculid caused by Bacille Calmette-Guerin vaccination requiring no antitubercular agents.IDCases · 2021Article
- Papulonecrotic tuberculid and Poncet disease: A case of multisystem delayed-type hypersensitivity in a patient withJAAD case reports · 2019Article
- Immune-mediated tuberculous uveitis - A rare association with papulonecrotic tuberculid.Indian journal of ophthalmology · 2019Article
- Perforating Granuloma Annulare Mimicking Papulonecrotic Tuberculid.Annals of dermatology · 2018Article
- A rare case of Hodgkin's lymphoma presenting with papulonecrotic tuberculid.BMJ case reports · 2017Article
- Revisiting tuberculids - Five year experience in a tertiary care teaching hospital.The Indian journal of medical research · 2016Article
- Papulonecrotic Tuberculid (PNT) Manifesting as Koebner Phenomenon; Hitherto Unreported Observation.Indian journal of dermatologyArticle
- Tuberculids: A Narrative Review.Indian dermatology online journalReview
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Authors and funding
5 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPapulonecrotic tuberculid (PNT) is said to be a hypersensitivity reaction to M. tuberculosis. Some reports indicate that organisms are demonstrable by polymerase chain reaction (PCR).
methodsWe describe 12 patients with PNT over 6 years. We reviewed the histopathologic features, clinical data and follow-up. PCR for M. tuberculosis DNA was done in all cases.
resultsThere were 7 men and 5 women. The ages ranged from 3-58 years. Upper limbs were commonly involved (8 cases). All patients had multiple papulonodular lesions, 5 showed ulceration and scarring. Mantoux test was strongly positive in all. Seven patients had systemic tuberculosis. On microscopy, necrosis was seen in 11 cases, varying from minimal to extensive. Epithelioid granulomas were common, except for 1 case with palisading and interstitial patterns. The infiltrate showed mostly lymphocytes, while 3 cases showed eosinophils. Vasculitis was seen in 8 cases. Two cases had dermal mucin, one also with interface dermatitis. This patient had concurrent LE. Mycobacterial DNA was detectable by PCR in 3 cases. Seven patients showed improvement/resolution of lesions on treatment.
conclusionsPNT is a rare disease. A positive PCR reiterates the question whether these are "tuberculids". PNT may be better classified as true cutaneous tuberculosis and patients screened for systemic disease.
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